{"title":"豚鼠精囊的电活动和原位自主药的作用","authors":"H. Takeda, H. Nakanishi","doi":"10.1540/jsmr1965.1.42","DOIUrl":null,"url":null,"abstract":"Studies were made of effects of hypogastric nerve stimulation on the electrical activity of guinea-pig seminal vesicle with extracellular silver microelectrodes in situ. Furthermore, the effects of several autonomic agents were also investigated. Junction potentials with facilitation were observed during repetitive stimulation of the hypogastric nerve, which were affected by intravenous administration of reserpine, bretylium tosylate, guanethidine, hexamethonium and pentolinium. On the other hand, atropine and α-blocking agents had no detectable effects. Intravenous administration of noradrenaline leads to periodic bursts of spike discharges accompanied with the contraction of seminal vesicle. The results suggested that seminal vesicle of guinea-pig may be innervated by hypogastric nerve such fashion as was deferens.","PeriodicalId":156233,"journal":{"name":"Japanese Journal of Smooth Muscle Research","volume":"45 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"ELECTRICAL ACTIVITY OF THE GUINEA-PIG SEMINAL VESICLE AND THE EFFECTS OF AUTONOMIC AGENTS IN SITU\",\"authors\":\"H. Takeda, H. Nakanishi\",\"doi\":\"10.1540/jsmr1965.1.42\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Studies were made of effects of hypogastric nerve stimulation on the electrical activity of guinea-pig seminal vesicle with extracellular silver microelectrodes in situ. Furthermore, the effects of several autonomic agents were also investigated. Junction potentials with facilitation were observed during repetitive stimulation of the hypogastric nerve, which were affected by intravenous administration of reserpine, bretylium tosylate, guanethidine, hexamethonium and pentolinium. On the other hand, atropine and α-blocking agents had no detectable effects. Intravenous administration of noradrenaline leads to periodic bursts of spike discharges accompanied with the contraction of seminal vesicle. The results suggested that seminal vesicle of guinea-pig may be innervated by hypogastric nerve such fashion as was deferens.\",\"PeriodicalId\":156233,\"journal\":{\"name\":\"Japanese Journal of Smooth Muscle Research\",\"volume\":\"45 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1900-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Japanese Journal of Smooth Muscle Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1540/jsmr1965.1.42\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Japanese Journal of Smooth Muscle Research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1540/jsmr1965.1.42","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
ELECTRICAL ACTIVITY OF THE GUINEA-PIG SEMINAL VESICLE AND THE EFFECTS OF AUTONOMIC AGENTS IN SITU
Studies were made of effects of hypogastric nerve stimulation on the electrical activity of guinea-pig seminal vesicle with extracellular silver microelectrodes in situ. Furthermore, the effects of several autonomic agents were also investigated. Junction potentials with facilitation were observed during repetitive stimulation of the hypogastric nerve, which were affected by intravenous administration of reserpine, bretylium tosylate, guanethidine, hexamethonium and pentolinium. On the other hand, atropine and α-blocking agents had no detectable effects. Intravenous administration of noradrenaline leads to periodic bursts of spike discharges accompanied with the contraction of seminal vesicle. The results suggested that seminal vesicle of guinea-pig may be innervated by hypogastric nerve such fashion as was deferens.
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