STAR(用富含纤维的营养饮料管理糖尿病的调查):一项泛印度调查,了解医生和患者对膳食纤维补充剂在2型糖尿病管理中的作用的看法

S. Kalra, N. Kapoor, S. Bhattacharya, Sambit Das, N. Deshpande, S. Kota, S. Shaikh
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引用次数: 0

摘要

目的:STAR调查的目的是了解医生对营养膳食纤维补充剂在2型糖尿病(T2DM)日常管理中的作用的知识、态度和看法。它还旨在比较服用高纤维补充剂和未服用高纤维补充剂的患者的血糖参数、能量和饱腹感水平的变化。方法:进行了两次横断面的泛印度调查。第一项研究是在152名医生中进行的,这些医生在治疗T2DM患者方面有5年以上的经验,每月治疗T2DM患者超过50名。调查采用了一份自我管理的纸质问卷。另一项调查是在3042名接受抗糖尿病药物治疗的2型糖尿病患者中进行的。这些患者被进一步分为霍利克斯糖尿病(HDP)组,其中包括1524名服用HDP纤维补充剂至少3个月的患者和非HDP组,其中包括1518名从未服用HDP的患者。结果:几乎所有的医生都给他们的2型糖尿病患者开富含纤维的营养补充剂,并认为膳食纤维在控制糖化血红蛋白(HbA1c)值、健康体重和胆固醇水平方面具有重要作用。医生看到的HDP的主要益处包括改善饱腹感水平和增加体力活动,降低糖化血红蛋白,空腹和餐后血糖,减少降糖药的剂量和/或数量。所有医生都建议提高患者和医生对2型糖尿病患者HDP益处的认识是很重要的。HDP组患者报告的HbA1c值在3个月时平均下降0.72,具有统计学意义(基线为8.04,3个月时为7.32)。相比之下,非hdp组的HbA1c从基线值8.15下降了0.61,无统计学意义。此外,患者报告体重在3个月内从基线值72.11 kg显著下降至69.11 kg。HDP组中有82%的患者体重减轻,而非HDP组在3个月内体重从基线值72.14 kg减少到71.46 kg。大约83%的患者报告在开始HDP后感觉饱腹时间更长,92.62%的患者报告在开始HDP后感觉更有活力。HDP的依从率为96%,满意率为75%。结论:高纤维补充剂配合患者现有的降糖治疗方案有可能降低T2DM患者的血糖参数和体重,同时增加饱腹感和能量水平。然而,这些结果需要在现实世界中进行长期临床研究来进一步评估。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
STAR (Survey for ManagemenT of DiAbetes with FibeR-rich Nutrition Drink): A Pan India Survey to Understand the Physician and Patient Perspective Regarding the Role of Dietary Fiber Supplement in the Management of Type 2 Diabetes
Objectives: The aim of the STAR survey was to understand the physicians’ knowledge, attitude and perception regarding the role of nutritional dietary fiber supplements in the daily management of type 2 diabetes mellitus (T2DM). It also aimed to compare the changes in glycemic parameters as well as energy and satiety levels between patients taking a high-fiber supplement and those not taking a fiber supplement. Methods: Two cross-sectional pan-India surveys were conducted. The first was among 152 physicians who had >5 years of experience in treating patients with T2DM and treated >50 patients with T2DM per month. A self-administered paper-based questionnaire was used for the survey. The other survey was conducted among 3,042 patients with T2DM who were receiving treatment with antidiabetics. These patients were further categorized into the Horlicks Diabetes Plus (HDP) group, which consisted of 1,524 patients who had consumed the HDP fiber supplement for a minimum of 3 months and the non-HDP group, which included 1,518 patients who had never consumed HDP. Results: Almost all physicians prescribed fiber-rich nutritional supplements to their patients with T2DM and believed that dietary fiber has an important role in managing glycated hemoglobin (HbA1c) values, healthy weight and cholesterol levels. Among the main benefits of HDP seen by physicians were improvement in satiety levels and increase in physical activity, reduction in HbA1c, fasting and postprandial glucose, and reduction in dose and/or number of hypoglycemic medications. All physicians recommended that it was important to increase awareness among patients as well as doctors regarding the benefits of HDP in patients with T2DM. Patients in the HDP group reported a mean decrease of 0.72 in their HbA1c value which was statistically significant at 3 months (8.04 at baseline to 7.32 at 3 months). In contrast, the non-HDP group showed a non-statistically significant decrease of 0.61 in HbA1c from a baseline value of 8.15. Furthermore, patients reported a significant decrease in weight of 3 kg in 3 months from baseline value of 72.11 kg to 69.11 kg. This reduction in weight was observed in 82% patients in the HDP group, while the non-HDP group showed an insignificant weight reduction from a baseline value of 72.14 kg to 71.46 kg in 3 months. About 83% of patients reported feeling full for longer periods of time and 92.62% reported feeling more energetic after starting HDP. The compliance and satisfaction rates with HDP were 96% and 75%, respectively. Conclusion: A high-fiber supplement taken along with patients’ existing antidiabetic treatment plan has the potential to decrease glycemic parameters and weight while increase the satiety and energy levels among patients with T2DM. However, these results need to be evaluated further with long-term clinical studies conducted in the real world. 
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