博伊德技术联合多西他赛/吉西他滨治疗骨转移性尤文氏肉瘤与肿瘤活性改善相关

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摘要

尤文氏肉瘤是一种主要影响儿童、青少年和年轻人的恶性骨肿瘤,全世界每百万人中有超过1.5例。大约20-25%的患者在诊断时出现转移性疾病,这通常对强化治疗有抵抗力。我们报告一例19岁男性癫痫患者,因左侧股骨远端骨折接受手术治疗后出现体重减轻、体积增大、疼痛、肿胀等症状,断层扫描显示50厘米肿瘤伴多处肺部病变,因此采用Boyd技术进行了关节解除术,组织病理学结果为Ewing肉瘤。随后被送往内科肿瘤科进行随访和辅助治疗,肺转移活动的临床和放射学均有显著改善。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Surgical Resection with Boyd Technique for Metastatic Ewing Sarcoma of the Bone Plus Docetaxel/Gemcitabine, Associated with Improved Outcomes in Tumor Activity
Ewing sarcoma is a malignant bone tumor that mainly affects children, adolescents and young adults with more than 1.5 cases per million worldwide. Approximately 20-25% of patients present metastatic disease at the diagnosis, that is often resistant to intensive therapy.We present the case of a 19-year-old male with history of epilepsy who started his condition with weight loss, increased volume, pain, swelling after receiving surgical treatment due to a left distal femur fracture, showing tomographic evidence of a 50-cm tumor with multiple lung lesions, so disarticulation was performed with the Boyd technique, obtaining histopathological result of Ewing’s Sarcoma, and was subsequently sent to the medical oncology service for follow-up and adjuvant treatment with significant clinical and radiological improvement in pulmonary metastatic activity.
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