A. Zyubin, E. Konstantinova, V. Slezhkin, K. Matveeva, I. Samusev, V. Bryukhanov
{"title":"荧光和振动光谱在脓毒症患者病理过程中血清白蛋白结构变形的应用","authors":"A. Zyubin, E. Konstantinova, V. Slezhkin, K. Matveeva, I. Samusev, V. Bryukhanov","doi":"10.1117/12.2295315","DOIUrl":null,"url":null,"abstract":"In this paper we perform results of conformational analysis of septic human serum albumin (HSA) carried out by Raman spectroscopy (RS), infrared (IR) spectroscopy and fluorescent spectroscopy. The main vibrational groups were identified and analyzed for septic HSA and its health control. Comparison between Raman and IR results were done. Fluorescent spectral changes of Trp-214 group were analyzed. Application of Raman, IR spectroscopy, fluorescent spectroscopy for conformational changes study of HSA during pathology were shown.","PeriodicalId":283327,"journal":{"name":"Biophotonics-Riga","volume":"7 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2017-12-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Application of fluorescent and vibration spectroscopy for septic serum human albumin structure deformation during pathology\",\"authors\":\"A. Zyubin, E. Konstantinova, V. Slezhkin, K. Matveeva, I. Samusev, V. Bryukhanov\",\"doi\":\"10.1117/12.2295315\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"In this paper we perform results of conformational analysis of septic human serum albumin (HSA) carried out by Raman spectroscopy (RS), infrared (IR) spectroscopy and fluorescent spectroscopy. The main vibrational groups were identified and analyzed for septic HSA and its health control. Comparison between Raman and IR results were done. Fluorescent spectral changes of Trp-214 group were analyzed. Application of Raman, IR spectroscopy, fluorescent spectroscopy for conformational changes study of HSA during pathology were shown.\",\"PeriodicalId\":283327,\"journal\":{\"name\":\"Biophotonics-Riga\",\"volume\":\"7 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2017-12-07\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Biophotonics-Riga\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1117/12.2295315\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biophotonics-Riga","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1117/12.2295315","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Application of fluorescent and vibration spectroscopy for septic serum human albumin structure deformation during pathology
In this paper we perform results of conformational analysis of septic human serum albumin (HSA) carried out by Raman spectroscopy (RS), infrared (IR) spectroscopy and fluorescent spectroscopy. The main vibrational groups were identified and analyzed for septic HSA and its health control. Comparison between Raman and IR results were done. Fluorescent spectral changes of Trp-214 group were analyzed. Application of Raman, IR spectroscopy, fluorescent spectroscopy for conformational changes study of HSA during pathology were shown.
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