腱鞘巨细胞瘤-特殊的MRI表现

A. Bratu, I. Sălcianu, A. Nicula, C. Zaharia, A. Marinescu
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摘要

摘要软组织巨细胞瘤(GCTST)通常起源于滑膜。它影响滑膜、浆液滑囊和肌腱隧道。最常见的定位是在手和前臂。解剖病理学上,GCTST被认为是由肿瘤细胞分布的细胞成纤维基质组成的。这种类型的肿瘤由单核复合体和破骨细胞样的巨大多核细胞组成,与骨水平的巨细胞肿瘤相似。在组织学上,一些作者认为GCTST是一种严格的良性肿瘤,由界限明确的多核组织细胞混合嗜酸性粒细胞、淋巴细胞和分散的纺锤形细胞组成,或其结构中有含铁血黄素沉积,肿瘤细胞无有丝分裂或异型性。其他作者认为GCTST是一种低级别肉瘤;由于组织学上与恶性纤维组织细胞瘤相似,故命名为“巨细胞型恶性纤维组织细胞瘤”。病例的女性患者,怀疑巨细胞肿瘤的肱桡肌肌腱鞘提出。这个肿瘤的MRI表现不典型。MRI检查包括一系列序列,T1和T2加权图像,脂肪抑制序列,在轴、矢状和冠状三个平面上进行。此外,检查是在静脉注射造影剂后进行的,当进行三维多平面序列时进行。最后的诊断是术后解剖病理检查,证实这是一个巨细胞瘤。我们提出这个病例的原因是其不常见的定位-前臂,以及它可能对手术治疗的兴趣。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Giant Cell Tumours of the Tendon Sheath – Particular MRI Aspect
Abstract Giant cell tumor of soft tissue (GCTST) is usually of synovial origin. It affects synovial membrane, serous bursae, and tendinous tunnels. The most common localizations are in the hands and forearms. Anatomopathological, GCTST is considered as being composed of a cellular fibroblastic stroma in which the tumor cells are distributed. This type of tumor is composed of a mononuclear complex and osteoclast-like giant multinucleated cells, similar to those found in the giant cell tumor at the bone level. Histologically, some authors consider that GCTST is a strictly benign tumor, consisting of welldefined multinucleated histiocytes admixed with eosinophils, lymphocytes and scattered spindleshaped cells, or hemosiderin deposits in its structure, and tumor cells do not have mitosis or atypia. Other authors consider that GCTST is a type of low-grade sarcoma; this entity was named “malignant fibrous histiocytoma, giant cell type” due to the histological similarity with malignant fibrous histiocytoma. The case of a female patient, suspected of giant cell tumor of the brachioradialis tendon sheath was presented. The MRI aspect of this tumor is not the typical one. The MRI examination consisted of a series of sequences, with T1 and T2 weighted images, fat suppression sequence, performed in all three planes, axial, sagittal, and coronal. Also, the examination was performed native, after the administration of intravenous contrast substance, when the 3D multiplanar sequences were performed. The final diagnosis was the post-operative anatomopathological examination, which confirmed that it was a giant cell tumor. We present this case for its less frequent localization - forearm, and the interest it might have in surgical treatment.
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