基于时变sir模型的COVID-19风险评估

Mehrdad Kiamari, G. Ramachandran, Quynh Nguyen, Eva Pereira, Jeanne Holm, B. Krishnamachari
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引用次数: 20

摘要

决策者需要数据驱动的工具来评估COVID-19的传播,并不断向公众通报其感染风险。我们提出了一种严格的混合模型和数据驱动的方法,以时变SIR流行病模型为基础进行风险评分,最终为每个社区生成简化的彩色编码风险水平。我们提出的风险评分Γt与目前健康的人在未来24小时内感染的概率成正比。我们展示了如何使用另一种有用的感染传播指标Rt来估计这种风险评分,Rt是随时间变化的平均繁殖数,它表明感染者依次感染的平均个体数。所提出的方法还允许以置信区间的形式量化Rt和Γt估计中的不确定性。我们努力的代码和数据已经开源,并正在应用于评估和传达洛杉矶市和县的感染风险。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
COVID-19 Risk Estimation using a Time-varying SIR-model
Policy-makers require data-driven tools to assess the spread of COVID-19 and inform the public of their risk of infection on an ongoing basis. We propose a rigorous hybrid model-and-data-driven approach to risk scoring based on a time-varying SIR epidemic model that ultimately yields a simplified color-coded risk level for each community. The risk score Γt that we propose is proportional to the probability of someone currently healthy getting infected in the next 24 hours based on their locality. We show how this risk score can be estimated using another useful metric of infection spread, Rt, the time-varying average reproduction number which indicates the average number of individuals an infected person would infect in turn. The proposed approach also allows for quantification of uncertainty in the estimates of Rt and Γt in the form of confidence intervals. Code and data from our effort have been open-sourced and are being applied to assess and communicate the risk of infection in the City and County of Los Angeles.
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