Dwi Rachmawaty Daswi, Arisanty Arisanty, St Mutmainnah Dewi Reski, Alfrida Monica Salasa, St. Ratnah
{"title":"面部剂型产品的配方和生理稳定性,它含有非洲叶提取物的Carbopol浓度的变化","authors":"Dwi Rachmawaty Daswi, Arisanty Arisanty, St Mutmainnah Dewi Reski, Alfrida Monica Salasa, St. Ratnah","doi":"10.32382/mf.v18i1.2299","DOIUrl":null,"url":null,"abstract":"African leaves (Vernonia amygdalina Del.) are plants that have benefits as natural antioxidants because it contain phenolic compounds including flavonoids that can wardoff free radicals. This study aims to formulate facial gel preparations from African leaf extracts to determine the stability of the physical quality of the preparations. African leaves are extracted using the maceratio method and then formulated into a facial gel made in three variations of the formula. Three gel formulas made with different carbopol concentrations are 0.5%, 1%, 2%. Physical quality testing of facial gel preparations is performed before and after the accelerated stability test (freeze thaw), including organoleptics, homogeneity tests, syneresis tests, pH tests, scatterpower tests and viscosity tests. Based on the results, formula II with 1 % carbopol concentration fulfilled almost all the requirement of the physical quality test carried out before and after the accelerated stability test excep for pH testing, for formula I with 0,5 % carbopol concentration and formula III with 2 % carbopol concentration only met homogenity,synerisis and viscosity test requirement.The result of statistical test showed the result of P>0,05 which means there is no significant difference from the test results before and after accelerateds storage.","PeriodicalId":190256,"journal":{"name":"Media Farmasi","volume":"1 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2022-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Formulasi Dan Stabilitas Mutu Fisik Sediaan Gel Wajah Yang Mengandung Ekstrak Daun Afrika Dengan Variasi Konsentrasi Carbopol\",\"authors\":\"Dwi Rachmawaty Daswi, Arisanty Arisanty, St Mutmainnah Dewi Reski, Alfrida Monica Salasa, St. Ratnah\",\"doi\":\"10.32382/mf.v18i1.2299\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"African leaves (Vernonia amygdalina Del.) are plants that have benefits as natural antioxidants because it contain phenolic compounds including flavonoids that can wardoff free radicals. This study aims to formulate facial gel preparations from African leaf extracts to determine the stability of the physical quality of the preparations. African leaves are extracted using the maceratio method and then formulated into a facial gel made in three variations of the formula. Three gel formulas made with different carbopol concentrations are 0.5%, 1%, 2%. Physical quality testing of facial gel preparations is performed before and after the accelerated stability test (freeze thaw), including organoleptics, homogeneity tests, syneresis tests, pH tests, scatterpower tests and viscosity tests. Based on the results, formula II with 1 % carbopol concentration fulfilled almost all the requirement of the physical quality test carried out before and after the accelerated stability test excep for pH testing, for formula I with 0,5 % carbopol concentration and formula III with 2 % carbopol concentration only met homogenity,synerisis and viscosity test requirement.The result of statistical test showed the result of P>0,05 which means there is no significant difference from the test results before and after accelerateds storage.\",\"PeriodicalId\":190256,\"journal\":{\"name\":\"Media Farmasi\",\"volume\":\"1 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-04-12\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Media Farmasi\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.32382/mf.v18i1.2299\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Media Farmasi","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.32382/mf.v18i1.2299","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Formulasi Dan Stabilitas Mutu Fisik Sediaan Gel Wajah Yang Mengandung Ekstrak Daun Afrika Dengan Variasi Konsentrasi Carbopol
African leaves (Vernonia amygdalina Del.) are plants that have benefits as natural antioxidants because it contain phenolic compounds including flavonoids that can wardoff free radicals. This study aims to formulate facial gel preparations from African leaf extracts to determine the stability of the physical quality of the preparations. African leaves are extracted using the maceratio method and then formulated into a facial gel made in three variations of the formula. Three gel formulas made with different carbopol concentrations are 0.5%, 1%, 2%. Physical quality testing of facial gel preparations is performed before and after the accelerated stability test (freeze thaw), including organoleptics, homogeneity tests, syneresis tests, pH tests, scatterpower tests and viscosity tests. Based on the results, formula II with 1 % carbopol concentration fulfilled almost all the requirement of the physical quality test carried out before and after the accelerated stability test excep for pH testing, for formula I with 0,5 % carbopol concentration and formula III with 2 % carbopol concentration only met homogenity,synerisis and viscosity test requirement.The result of statistical test showed the result of P>0,05 which means there is no significant difference from the test results before and after accelerateds storage.