骨结核-文献回顾和少数病例报告

Dr. C. Sumalata, Dr. Arundhathi
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引用次数: 1

摘要

在印度,肺外结核占肺结核总数的15%。骨性结核构成骨和关节结核,由肺或其他内脏或淋巴结病灶的血源性扩散引起。结核性骨髓炎由Nelatoo(1837)描述;Rokitansky(1884)给出了组织学形态学;Koster(1869)发现关节结核结节;以及Volkmann(1879)的滑膜结核。病例1:一个相对罕见的肩关节结核病例,被诊断为中年农民,经过适当的疼痛和不能移动的历史。对他进行了适当的放射图像调查,该病例最终对抗结核治疗有反应。病例2:一例肋骨骨髓炎被诊断时,年轻的女士只有一个疼痛的投诉下胸部右侧。在她出现脓胸后,诊断为结核病,并对相同的脓液进行了结核病DNA检测。抗结核治疗开始后疼痛减轻,症状缓解。她也做过手术。病例3一位年轻女士主诉左腕长时间疼痛和肿胀。MRI显示远端腕骨骨髓水肿伴关节软骨缺失,跖骨、掌骨基部、头跖骨和第三掌关节基部有少量糜烂。免疫球蛋白释放试验(IGRA)结果为阳性,支持结核病的诊断。给予抗结核药物治疗,效果良好。病例4:一名中年男性,腰痛3年,经脊柱MRI诊断为L5 -S1部位Potts脊柱。他开始服用抗结核药物,效果很好。所有病例均被诊断为原发性肺部受累。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Skeletal Tuberculosis- Review of Literature and Few case reports
Extrapulmonary tuberculosis forms 15% of total tuberculosis in India. Skeletal tuberculosis which constitutes bone and joint tuberculosis, results from haematogenous spread from a pulmonary or other visceral or lymph node focus. Tuberculosis osteomyelitis was described by Nelatoo (1837); histologic morphology was given by Rokitansky (1884); tuberculosis nodule in a joint was seen by Koster (1869); and synovial tuberculosis by Volkmann (1879). Case No. 1: A case of Shoulder joint Tuberculosis which was relatively rare, was diagnosed in a middle aged farmer after taking proper history of pain and inability to move. He was investigated appropriately with radiological images and the case eventually responded to the anti-tuberculosis treatment. Case No. 2: A case of rib osteomyelitis was diagnosed when the young lady had only a complaint of pain in lower chest right side. The diagnosis of TB was reached after she had empyema and the same pus was tested for TB DNA. The decrease in pain and relieve of symptoms noticed after the initiation of treatment with Anti tuberculous treatment. She had surgical intervention for the same. Case No. 3 A young lady complained of pain and swelling in left wrist for a long duration. MRI showed bone marrow oedema in distal row of carpal bones with loss of articular cartilage and small erosion noted in trapezoid, base of metacarpal and capitates and base of third metacarpal joint. The diagnosis of tuberculosis was supported with Immunoglobulin Releasing Assay (IGRA) which was positive. Anti tuberculous drugs were given, and she responded well. Case No. 4 A middle aged man who was suffering from low back ache from 3 years had been diagnosed as Potts spine at L5 –S1 with the help of MRI spine. He was started with Anti tuberculosis drugs and he responded well. All the cases were also worked up for primary pulmonary involvement.
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