辅助通用技术后围产期后果的比较方面

O. Ishchak
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引用次数: 0

摘要

目的:探讨辅助遗传技术对单胎和多胎分娩围产儿结果的影响。材料和方法。为确定目的,对346例经辅助基因技术诱导妊娠组(其中多胎组134例)和415例自然妊娠组(其中多胎组142例)的活产患儿进行了分析。新生儿状态分析发现,与非自愿妊娠相比,诱导单核细胞增多时出现更多的疾病:出生时窒息(4.7%对1.1%,p< 0.05)、新生儿黄疸(31.6%对18.6%,p< 0.05)、脑室内出血(3.3%对0.73%,p< 0.05)。在辅助遗传技术后的多胎新生儿中也有较多的出生时窒息、新生儿黄疸、呼吸窘迫综合征、脑室内出血,但没有发现统计学上可靠的差异。本组患儿出现宫内发育迟缓(29.3%)、出生时窒息(90.5%)、神经系统改变(53.6%)的发生率高于所有患儿。辅助遗传技术并不能增加果实发育先天异常的频率,也不能提高围产期发病率。更常见的是,一个大的值有婚前的婚姻背景,不孕的原因,诊断和治疗的效率,以及辅助遗传技术的使用程序的变体。辅助基因技术后的多胎会增加胎盘功能障碍和胎儿延迟的风险,从而对分娩的围产儿结果产生负面影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Comparative aspects of perinatal consequences after auxiliary genesial technologies
The objective: to study influence of auxiliary genesial technologies on the perinatal results of delivery at a singleton and multifetation. Materials and methods. For the decision of the put purpose there was the conducted analysis of birth 346 children – in the group of the induced pregnancy after auxiliary genesial technologies (from them 134 in the group of multifetation) and 415 living children in the group of spontaneous pregnancy (from them 142 in the group of multifetation). Results. The analysis of the state of new-born rotined that at the induced monocyesis the followings pathosiss meet more frequent, than at involuntary pregnancy: asphyxia at birth (4,7% against 1,1%, p<0,05), neonatal icterus (31,6% against 18,6%, p<0,05), intraventricular hemorrhage (3,3% against 0,73%, р<0,05). At multifetation after auxiliary genesial technologies at new-born also more frequent registered asphyxia at birth, neonatal icterus, respirator distress-syndrome, intraventricular hemorrhage, however statistically reliable differences it is not discovered. By disorders which meet more frequent than all, this group of children had a delay of intrauterine development (29,3%), asphyxia at birth (90,5%), neurological changes (53,6 %). Conclusions. Auxiliary genesial technologies are not instrumental in the increase of frequency of innate anomalies of development at a fruit, and also to growth of level of perinatal morbidity. Far more frequent a large value has a premonstratensian background of matrimonial pair, reasons of nfertility, efficiency of diagnostics and treatment, and also variant of the in-use programs of auxiliary genesial technologies. The presence of multifetation after auxiliary genesial technologies promotes the risk of development of placenta disfunction and delay of fetation, that negatively influences on the perinatal results of delivery.
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