V. Shatilo, I. Antonyuk-Shcheglova, S. Naskalova, O. Bondarenko, Oksana Hrib, Dmitry Krasnienkov, A. Pisaruk
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Quercetin effect on endogenous factors of cardiovascular risk and ageing biomarkers in elderly people
Abstract. The reason for this study was the lack of literature data on the quercetin effect on endogenous cardiovascular risk factors and ageing biomarkers in elderly patients with metabolic syndrome (MS). The results of this study showed that quercetin has a favourable corrective effect on endogenous cardiovascular risk factors in elderly patients with MS, quercetin course increases the resistance of the elderly to the effects of hypoxia, long-term quercetin use (within 3 months) leads to lengthening of telomeres and a decrease in metabolic age, which indicates the presence of a geroprotective effect. The obtained results of the quercetin course application influence on the telomere length show the expediency of continuing the study of this drug as an effective geroprotective agent.
Keywords: quercetin; metabolic syndrome; endogenous factors; ageing biomarkers; geroprotective effect
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