泗水市活体亲属肾移植患者的存活率

Decsa Medika, Aditiawardana Aditiawardana, Pranawa Pranawa, D. Santoso, W. Widodo, Chandra Irwanadi Mohani
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摘要

摘要背景在过去的三十年中,移植患者的生存预后有所改善。移植物和患者的短期和长期生存仍在广泛研究中。影响生存率的因素有年龄、性别、糖尿病、免疫抑制治疗等。目的了解移植后患者1年、3年和5年的生存率。方法对1996 - 2016年门诊肾移植患者67例进行描述性分析。收集的数据用SPSS统计软件进行分析,采用Kaplan-Meier曲线观察生存率。结果1年、3年、5年生存率分别为100%、97%、94%。老年和非老年患者移植后1年生存率均为100%,移植后3年生存率分别为100%和94.7%,移植后5年生存率分别为100%和89.5%。男、女患者1、3、5年生存率分别为100%、96.3%对100%、92.6%对100%。与非糖尿病患者相比,糖尿病患者1年、3年和5年的生存率分别为100%、96.5%对100%、93%对100%。移植后第一年他克莫司与环孢素的生存率均为100%,第三年为97.1% vs 97%,第5年为97.1% vs 90.9%。结论肾移植患者术后1、3、5年生存率分别为100%、97%、94%。与较高生存率相关的因素有老年患者、女性、糖尿病以及在免疫抑制剂治疗方案中使用环孢素。关键词:肾移植;生存
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Survival Rate of Living Related Kidney Transplant Patients in Surabaya
Abstract Background The survival outcome of transplant patients have improved in the past three decades. The short and long term survival of graft and patients are still being widely studied. Many factors affect the survival rate such as age, gender, diabetes mellitus, and immunosuppressive therapy. Objective The study aim to provide patients’ survival rates 1, 3, and 5 years after transplant. Methods The study used descriptive approach on 67 kidney transplant patients undergoing outpatient treatment from 1996 to 2016. The data collected was analyzed using SPSS with the Kaplan-Meier curve to observe the survival rate. Result The survival rate of patients in 1, 3, and 5 years were 100%, 97%, and 94% respectively. The survival rate in geriatric and non-geriatric patients in the first year post-transplantation was both 100%, the third year post-transplantation survival rate were 100% and 94.7%, and the five year post-transplantation survival rate were 100% and 89.5%. The 1, 3, and 5 year survival rate for male and female patients were both 100%, 96.3% vs 100%, and 92.6% vs 100% respectively. Compared to their non-diabetic counterparts, diabetic patients’ survival rate in 1, 3, and 5 years were both 100%, 96.5% vs 100%, and 93% vs 100% respectively. The survival rate of patients receiving tacrolimus vs cyclosporine were both 100% in the first year, 97.1% vs 97% in the third year, and 97.1% vs 90.9% in the fifth year after transplant. Conclusion The survival rate of kidney transplant patients in 1, 3, and 5 year after transplant were 100%, 97%, and 94%. Factors linked to higher survival rate were geriatric patients, female gender, diabetes, and the use of cyclosporine in the immunosuppressant therapy regimen.   Keyword: kidney transplantation, survival
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