Inflammatory Bowel Disease, Ulcerative Colitis, Crohns Disease or Indeterminate Colitis? Diagnostic Challenge

Usually diffuse disease, but may show rectal sparing Toxic dilation may be present Morphological Microscopic Features Seen in Indeterminate Colitis Extensive ulceration with a sharp transition to normal adjacent mucosa. Transmural lymphoid inflammation, with an absence of lymphoid aggregates. Absence of well-defined, epithelioid granulomas distant from crypts. Multiple squat V-shaped ulcers, lacking surrounding inflammation.