Directly Observed Therapy for the Treatment of Tuberculosis in Baltimore

This chapter provides a summary of a landmark study in systems-based practice. Is directly observed therapy (DOT) effective in lowering the rates of tuberculosis (TB) in communities? Starting with this question, it describes the basics of the study, including funding, study location, who was studied, how many patients, study overview, study intervention, follow-up, endpoints, results, and criticism and limitations. The chapter briefly reviews other relevant studies and information, discusses implications, and concludes with a relevant clinical case.