洗精至宫内人工授精间隔时间对妊娠率的影响

E. Kılıçdağ
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引用次数: 3

摘要

背景:本研究的目的是评估从洗精到宫内人工授精的间隔时间对IUI结果的影响。材料和方法:本研究是对2011年1月至2011年12月Baskent大学医学院妇产科1125个周期的前瞻性研究。结果:在1125个周期中,202个周期小于30分钟,367个周期为30 ~ 59分钟,381个周期为60 ~ 89分钟,114个周期为90 ~ 119分钟,61个周期为120 ~ 180分钟。妊娠率分别为% 4.5%、% 7.9%、% 11%、%8.8、% 11.5%。我们再次分析<30分钟组和其他组,我们发现差异达到统计学显著水平(%4.5 vs %9.5)(p: 0.01)。在总活动精子数为310x106的预后良好的患者中,授精时间<30分钟的患者的妊娠率低于其他患者(%5.2 vs %10.1)(p: 0.024)。结论:我们的研究结果表明,如果洗涤精子能在37℃下孵育至少30分钟,则妊娠率最佳。最长可达180分钟的时间不会影响怀孕率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
THE EFFECT OF INTERVALS FROM SPERM WASH TO INTRA UTERINE INSEMINATION (IUI) T‹ME ON PREGNANCY RATE
Background: The aim of our study was to assess the influence of intervals from sperm wash to intra uterine insemination on the IUI outcome. Material and methods: This was prospective study of 1125 cycles in Obstetrics and Gynecology Department of Baskent University Medical Faculty between January 2011 and December 2011. Results: In totally 1125 cycles IUI performed within < 30 minute in 202 cycle, 30-59 minute in 367 cycle, 60-89 minute in 381 cycle, 90-119 minute in 114 cycle, 120-180 minute in 61 cycle. Pregnacy rate was %4.5,%7.9,%11,%8.8, ve %11.5 respectively. We reanalyzed <30 minutes and other groups again we found that the difference reached statically significant level (%4.5 vs %9.5)(p: 0.01). In good prognostic patients with total motile sperm count was 3 10x106, pregnancy rates were lower in patients whose inseminated in <30 minute than the others (%5.2 vs %10.1)(p: 0.024). Conclusion: The results of our study showed that if a washing sperm can be incubated minimum 30 minute at 37 C the pregnancy rate is optimum. The longer period up to 180 minute doesn't compromise the pregnancy rate.
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