使用形状记忆聚合物泡沫的生物医学设备治疗颅内动脉瘤

Jingyu Wang, Jishan Luo, Robert Kunkel, Yingtao Liu, B. Bohnstedt, Chung-Hao Lee
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引用次数: 2

摘要

介绍了一种利用形状记忆聚合物(SMP)泡沫开发的用于颅内动脉瘤(ICAs)血管内治疗的新型医疗器械。SMP泡沫的制备,表征和实验研究,以更好地了解其潜在的血管内栓塞的ICAs。成功合成了聚氨酯基SMP并对其进行了表征。SMP泡沫采用铸造成型制造,并使用电热触发机制进行表征,以充分了解其形状恢复能力。这项工作的成功完成将为开发治疗颅内动脉瘤的新型生物医学设备和为未来的动物研究制定最佳的释放程序奠定坚实的基础。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Biomedical Devices Using Shape Memory Polymer Foams for Treatment of Intracranial Aneurysms
This paper presents a novel medical device developed using shape memory polymer (SMP) foams for the endovascular treatment of intracranial aneurysms (ICAs). The SMP foam is fabricated, characterized, and experimentally investigated to better understand their potential for endovascular embolization of ICAs. Polyurethane-based SMP is successfully synthesized and characterized. The SMP foam is manufactured using cast molding, and characterized using an electro-thermal triggering mechanism to fully understand their shape recovery capability. The successful completion of this work will serve as a solid foundation for the development of new biomedical devices to treat intracranial aneurysms and develop an optimal releasing procedure for future animal study.
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