尼日利亚大学Ituku-Ozalla Enugu教学医院诊断为多形性腺瘤(PA)的肿瘤的描述性分析

O. James, Chukwuemeka Okechi Uchenna, Amaechi Agu Kenneth, Chukwuemeka Ezeanolue Basil
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引用次数: 1

摘要

涎腺多形性腺瘤是一种生长缓慢的无痛良性肿瘤,其组织学特征是上皮和肌上皮成分混合。它发生在大唾液腺和小唾液腺,腮腺是大唾液腺最常见的部位,而上颚是小唾液腺最常见的部位。本研究旨在评估尼日利亚埃努古伊图库/奥扎拉尼日利亚大学教学医院多形性腺瘤的临床表现。回顾性分析2009年1月至2014年12月6年间所有多形性腺瘤患者的临床资料。从患者档案中检索相关信息。数据分析采用SPSS version 23;质变量比较采用卡方检验。37例大小唾液腺多形性腺瘤(患病率41.1%)符合纳入标准。大多数病例发生在女性。患者平均年龄为38.2岁,标准差为16.4岁。肿瘤出现时的平均持续时间为39.4个月。腮腺是最常见的部位。术后并发症为面神经麻痹。大多数肿瘤发生在左侧。多形性腺瘤表现为无痛性肿胀,多见于女性。发生的高峰年龄是在生命的第四个十年。手术切除是治疗的主要方法。许多患者在肿瘤开始生长多年后才出现。关键词:多形性腺瘤,唾液腺,良性肿瘤。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Descriptive analysis of neoplasias diagnosed as pleomorphic adenoma (PA) that presented at the University of Nigeria Teaching Hospital Ituku-Ozalla Enugu
Pleomorphic adenoma of the salivary gland is described as a slow growing painless benign tumor characterized histologically by its mixed appearance with epithelial and myoepithelial components. It occurs in both the major and minor salivary glands with the parotid gland as the commonest site for the major gland while the palate is the commonest site for the minor glands. This study was conducted to evaluate the clinical presentation of pleomorphic adenoma seen in the University of Nigeria Teaching Hospital Ituku/Ozalla, Enugu, Nigeria. Records of all the patients with pleomorphic adenoma seen in the clinics within a six year period (January 2009 to December 2014) were retrospectively reviewed. Relevant information retrieved from the patients’ file. Data was analyzed using SPSS version 23; qualitative variables were compared using chi-square test. A total of 37 cases (prevalence = 41.1%) of pleomorphic adenoma of the major and minor salivary gland met the required criteria for inclusion in the study. Majority of the cases occurred in females. The mean age of the patients was 38.2 and standard deviation was 16.4. The mean duration of the tumor at presentation was 39.4 months. Parotid gland was the commonest site. Postoperative complication seen was facial nerve palsy. Most of the tumors occurred on the left side. Pleomorphic adenoma present as a painless swelling is seen more in our environment among women. The peak age of occurrence is in the 4th decade of life. Surgical excision is the mainstay of treatment. Many of the patients presented years after the onset of tumor growth. Key words: Pleomorphic adenoma, salivary gland, benign tumors.
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