Human Mesenchymal Stem Cells Osteogenic Differentiation on Dental Barrier Membrane

In the field of tissue engineering, there are biodegradable bone implants with biocompatible synthetic polymers that provide successful results in many areas. Dental barrier membranes are bioabsorbable polylactide (PLA) membranes designed for use in many applications of guided bone regeneration (GBR). It provides a structure designed to attract, capture and retain fibroblasts and epithelial cells while protecting the area around the tooth for the development of bone and periodontal supporting tissue. The aim of this study was to evaluate the properties of dental barrier membranes that inhibit cell migration and promote bone formation differentiation using bone marrow stem cells (BMSCs) with high differentiation and proliferation properties. As a result of the study, characterization studies and cell viability experiments of the Synthetic Barrier Membrane product were carried out, and it was observed that it had a positive effect on the adherence and viability of the BMSCs.