BİR SİMENTAL İNEKTE REKTAL FİBROMATOZİS

Bir Simental inekte rektal fibromatozis Ozet: Bu olayda 4 yasli Simental irki inekte rektum bolgesinde gozlenen cok sayidaki tumoral kitlelerden dolayi rektal muayeneyi zorlastiran ve operasyonuna karar verilen fibromatozis olgusunun klinik ve patolojik yonden incelenmesi amaclandi. Hayvanda dogumu izleyen donemde rektal muayene yapilmak istendiginde rektum cevresinde zamanla sayi ve hacimleri artan kitleler gozlendi. En buyugu 6,5 cm capinda yuvarlak ve 4x3x1,4cm buyuklugunde oval, cesitli buyuklukte 14 adet kati esnek kivamda, beyaz renkli kitlelere rastlandi. Kitlelerin bazilari deri ve cogunlukla mukoza ile kapli oldugu dikkati cekti. %10’luk tamponlu formaldehit ile tespit edilerek parafine gomulen ve 5 µm kalinliginda kesitler alinan dokular, Hematoksilen-Eosin (H-E) ve Van Gieson ile ayrica immunohistokimyasal (IHK) olarak sitokeratin ve vimentin ile boyandi. H-E kesitli dokulardaki tumoral kitlenin tipik anafor tarzinda yerlesmis fibroblast ve fibrositlerden olustugu, yapilan IHK boyamada ise vimentin pozitif ve sitokeratin negatif olarak gozlendi. Bu olgudaki gozlenen makroskobik, mikroskobik ve IHK’sal bulgular kaudal rektumda fibromatozis olgusu ile uyumlu bulunmustur. Anahtar kelimeler: Inek, rektum, fibroma Rectal fibromatosis in a Simmental cow. Abstract: In this case, it was aimed to investigate the clinical and pathological aspects of fibromatosis which make difficult rectal examination due to multiple tumoral masses observed in a 4-year-old Simmental–breed at rectum. Period of after the birth, the masses were seen around the rectal area of the cow when rectal examination was carried out. The number and volume of masses increased with time.The shapes of masses were round and oval and the largest size were 6.5 cm in diameter and 4 x 3 x 1.4 cm respectively. Totally 14 masses, covered with skin and mucosal membrane were found. Cut surface were whitish colored and solid-flexible in consistency. The tissues were fixed with 10% buffered formaldehyde and embedded in paraffin and sections with a thickness of 5 μm were stained with hematoxylen-eosin (H&E) and Van Gieson and immunohistochemical (IHC) with cytokeratin and vimentin.Tumor tissue in H&E sections consisted of fibroblasts and fibrocytes located in the typical herringbone pattern. Tumoral cells were vimentin-positive and cytokeratin-negative in IHC staining.Macroscopic, microscopic and IHC findings, in this case, were found to be consistent with the presence of fibromatosis in the caudal rectum. Key words: Cow, rectum, fibroma