Association between Anthropometric indices and Cardiometabolic Risk Factors among Women with Primary Infertility

Background: Cardiometabolic risk factors are commonly associated with women with infertility. The study evaluated the association between anthropometric indices and cardiometabolic risk factors in women with primary infertility. Methods: Two-hundred and sixteen (216) women with primary infertility underwent simple anthropometric measurement including waist circumference (WC), waist-to-height ratio (WHtR), body mass index (BMI), body adiposity index (BAI) and abdominal volume index (AVI). Blood pressure was assessed using an automated BP monitor and fasting blood samples were collected. Cardiometabolic risk factors were defined according to the NCEP-ATP III criteria. Receiver Operating Characteristic (ROC) curve and logistic regression analyses were used to evaluate associations Results: The mean age of the study participants was 30.3 years and the median duration of infertility was 3.0 (2.0-4.0 interquartile range). The prevalence of hypertension was 22.2%. Metabolic syndrome, hyperglycemia, and dyslipidemia were presents among 23.1%, 32.4%, and 48.1%, respectively. BMI (between 25.8Kg/m2 and 28.0 Kg/m2), strongly predicted hyperglycemia, MetS, and dyslipidemia. Additionally, the range of optimal cut-off values of central obesity indices including WC (84.0cm to 90.0 cm), WHR (0.85-0.89 cm/cm), WHtR (0.52-0.61 cm/cm) and AVI (14.3 to 16.5) better predicted hyperglycaemia, MetS and dyslipidaemia. Only BMI and BAI were significant predictors of hypertension. Conclusion: Cardiometabolic risk factors including hypertension, hyperglycemia, dyslipidemia and MetS are high among women with primary infertility. BMI proved superior in predicting cardiometabolic risk factors among primary infertile women.