U Demme, K Günther, R Werner, G Schwachula, R Kehnscherper, G Stein, L Feistel, W Junge
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引用次数: 0
摘要
对吸附剂Wofatit Y 88 (VEB Chemiekombinat Bitterfeld)与Hämoresin (B. Braun, Melsungen, FRG)吸附剂SKN-2K(苏联)和自己的产品Wofatit UH 91的吸附性能进行了比较。吸附剂分别为甲喹酮、吡啶酮、巴比妥和苯巴比妥。该调查已在单通道系统中进行，与临床实践条件的关系为1:25。紫外-可见光谱法测定了吸附量的浓度。结果表明，Wofatit y88在吸附量和吸附速度上均优于Hämoresin。对于所有药物，Wofatit Y 88优于UH 91。
[In vitro studies of the adsorption behavior of Wofatit Y 88 in relation to various drugs].
The adsorber Wofatit Y 88 (VEB Chemiekombinat Bitterfeld) was tested regarding its adsorption properties in comparison with Hämoresin (B. Braun, Melsungen, FRG) Hemosorbent SKN-2K (USSR) and the own product Wofatit UH 91. As adsorptives the hypnotics Metaqualon, Pyrithyldion, Crotylbarbital and Phenobarbital were used. The investigation have been performed in a single-pass system in a relation of 1:25 to the clinical practice conditions. The concentration measurements to the estimation of adsorbed amounts were made by UV-VIS spectrometry. It was found that Wofatit Y 88 is superior to Hämoresin with regard to adsorbed amounts and adsorption speed. For all drugs Wofatit Y 88 was superior to UH 91.
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