{"title":"不同强度体力负荷对肝酶活性及肝细胞增殖的影响","authors":"Malyshev Ii, Romanova Lp, Vorob'eva Ov","doi":"10.17352/ojh.000008","DOIUrl":null,"url":null,"abstract":"The paper establishes the relationship between enzymatic activity and the proliferation of hepatocytes. Low-intensity physical activity is shown not to influence the activity of hepatocytes’ enzymes and their proliferation. Hard work results in decreased activity of redox enzymes; at the same time, the proliferation of hepatocytes is inhibited for a long time. The most favorable is moderate load, which leads to the activation of oxidative-reducing enzymes and increases the number of binucleated hepatocytes, which persist for a long time after the end of the experiment.","PeriodicalId":288820,"journal":{"name":"Open Journal of Hepatology","volume":"41 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2022-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The effect of physical load of varying intensity on the activity of liver enzymes and hepatocytes’ proliferation\",\"authors\":\"Malyshev Ii, Romanova Lp, Vorob'eva Ov\",\"doi\":\"10.17352/ojh.000008\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The paper establishes the relationship between enzymatic activity and the proliferation of hepatocytes. Low-intensity physical activity is shown not to influence the activity of hepatocytes’ enzymes and their proliferation. Hard work results in decreased activity of redox enzymes; at the same time, the proliferation of hepatocytes is inhibited for a long time. The most favorable is moderate load, which leads to the activation of oxidative-reducing enzymes and increases the number of binucleated hepatocytes, which persist for a long time after the end of the experiment.\",\"PeriodicalId\":288820,\"journal\":{\"name\":\"Open Journal of Hepatology\",\"volume\":\"41 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-10-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Open Journal of Hepatology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.17352/ojh.000008\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Open Journal of Hepatology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.17352/ojh.000008","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The effect of physical load of varying intensity on the activity of liver enzymes and hepatocytes’ proliferation
The paper establishes the relationship between enzymatic activity and the proliferation of hepatocytes. Low-intensity physical activity is shown not to influence the activity of hepatocytes’ enzymes and their proliferation. Hard work results in decreased activity of redox enzymes; at the same time, the proliferation of hepatocytes is inhibited for a long time. The most favorable is moderate load, which leads to the activation of oxidative-reducing enzymes and increases the number of binucleated hepatocytes, which persist for a long time after the end of the experiment.