孟加拉国一家三级医院2型糖尿病患者代谢综合征的发生率

M. Chowdhury, B. Atiquzzaman, Md. Afjal Hossain, M. Kabir, Tanvir Adnan, Marufa Yasmin
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摘要

背景:代谢综合征作为一种公认的冠心病危险因素,已经引起了人们的关注。但代谢综合征与2型糖尿病的关系以及代谢综合征的独立作用尚不清楚。为了评估2型糖尿病人群中代谢综合征的状况及其预测2型糖尿病的能力,并与常规卒中危险因素相结合,本研究计划进行。方法:采用连续随机抽样方法对100例2型糖尿病患者进行描述性观察研究。患者通过适当的病史、临床检查和必要的调查来诊断。结果值通过人体测量、血压、血脂异常和血糖来测量。结果:100例2型糖尿病患者中,家庭主妇女性占64%(41%),差异有统计学意义(p < 0.001),平均±SD为58±12.24岁,年龄范围32 ~ 85岁。约30%的人有2型糖尿病家族史,28%的人有吸烟史。其中,31%的患者有高血压,28%的患者有低HDL,差异有统计学意义(p<0.001),但46%的患者有高甘油三酯水平,差异无统计学意义。女性中心性肥胖占比超过一半(53.12%),男性中心性肥胖占比仅为16.67%,性别差异有统计学意义(p=0.04)。2型糖尿病患者代谢综合征发生率较高(68%),差异有统计学意义,其中女性占48%,男性占20%。代谢综合征患者中枢性肥胖36例(52.94%),女性为主32例(88.89%);高血压28例(4118%),男性为主16例(57.14%);高甘油三酯血症44例(64.70%),女性为主26例(59.09%);低HDL血症22例(32.35%),女性为主16例(72.73%)。结论:女性发生代谢综合征的频率为男性的两倍多(48%)。中心性肥胖和低HDL在女性中比在男性中更为普遍,而高血压在男性中更为显著。因此,我们有理由得出结论,女性更容易患代谢综合征,心血管疾病发病率和死亡率更高。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Frequency of Metabolic Syndrome in Type 2 Diabetes Mellitus in a Tertiary Care Hospital of Bangladesh
Background: As a well-established risk factor for coronary heart disease, Metabolic Syndrome was already encountered. But the relationship between Metabolic Syndrome and Type 2 Diabetes Mellitus and the independent contribution of Metabolic Syndrome remained unclear. To evaluate the status of metabolic syndrome in the Type 2 diabetic population and for their ability to predict Type 2 Diabetes Mellitus, in parallel with conventional stroke risk factors, this study was planned. Methods: A hospital-based descriptive observational study was conducted in 100 patients with Type 2 Diabetes Mellitus who were selected by consecutive random sampling techniques. Patients were diagnosed through proper history, clinical examination, and necessary investigations. The outcome values were measured in anthropometric measurements, blood pressure, dyslipidemia, and blood glucose. Results: Among 100 patients with Type 2 Diabetes Mellitus, (64%) were females who were housewives (41%) with significant difference (p < 0.001) and Mean± SD was 58±12.24 yrs ranging from 32-85 years. About 30% had a positive family history of Type 2 Diabetes Mellitus and 28% tobacco abuse. Of the total, 31% of patients had high blood pressure, and 28% had low HDL with a significant difference (p<0.001), but 46% had high triglyceride levels, which was not significant. More than half (53.12%) females showed central obesity, while only 16.67% had central obesity among males, and it showed a significant difference (p=0.04) in both sex. There was a high frequency of Metabolic Syndrome in a patient with Type 2 Diabetes Mellitus (68%) with a significant difference, and 48% were female, and 20 % were male. In patients of Metabolic Syndrome, central obesity was found in 36(52.94%) patients where females were predominantly affected 32(88.89%), hypertension found in 28(4118%) patients where male were predominantly affected 16(57.14%) patients, hypertriglyceridemia found in 44(64.70%) patients where a female was predominantly affected 26(59.09%) patients and low HDL found in 22(32.35%) patients where a female was predominantly affected 16(72.73%). Conclusion: The frequency of Metabolic Syndrome was more than double in women (48%). Central obesity and low HDL were significantly more prevalent in women than men, where hypertension was significant in men. So it would be reasonable to conclude that women are more likely to suffer from Metabolic Syndrome from cardiovascular morbidity and mortality.
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