S. Petrova, Nikol Mazhdrakova, S. Todinova, V. Strijkova, M. Zhiponova, S. Krumova
{"title":"荆芥提取物对氧化应激下红细胞形态的保护作用","authors":"S. Petrova, Nikol Mazhdrakova, S. Todinova, V. Strijkova, M. Zhiponova, S. Krumova","doi":"10.3390/ecb2023-14086","DOIUrl":null,"url":null,"abstract":".net/. Abstract: We show that an extract from catmint ( Nepeta nuda L.) flowers is not hemotoxic and does not alter erythrocytes’ morphology. H 2 O 2 -induced oxidative stress leads to an increase in lipid peroxidation, accompanied by a reduction in the number of biconcave cells and an increase in the number of echinocytes. Pre-treatment of erythrocytes with this extract does not reduce the lipid peroxidation level; however, it results in partial restoration of the relative abundance of biconcave cells and a respective reduction in the echinocytes’ quantity. Our data reveal the concentrations at which the examined extract exhibits a protective effect on erythrocytes’ morphology under the condition of H 2 O 2 -induced oxidative stress.","PeriodicalId":265361,"journal":{"name":"The 2nd International Electronic Conference on Biomedicines","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Nepeta nuda L. Plant Extract Preserves the Morphology of Red Blood Cells Subjected to Oxidative Stress\",\"authors\":\"S. Petrova, Nikol Mazhdrakova, S. Todinova, V. Strijkova, M. Zhiponova, S. Krumova\",\"doi\":\"10.3390/ecb2023-14086\",\"DOIUrl\":null,\"url\":null,\"abstract\":\".net/. Abstract: We show that an extract from catmint ( Nepeta nuda L.) flowers is not hemotoxic and does not alter erythrocytes’ morphology. H 2 O 2 -induced oxidative stress leads to an increase in lipid peroxidation, accompanied by a reduction in the number of biconcave cells and an increase in the number of echinocytes. Pre-treatment of erythrocytes with this extract does not reduce the lipid peroxidation level; however, it results in partial restoration of the relative abundance of biconcave cells and a respective reduction in the echinocytes’ quantity. Our data reveal the concentrations at which the examined extract exhibits a protective effect on erythrocytes’ morphology under the condition of H 2 O 2 -induced oxidative stress.\",\"PeriodicalId\":265361,\"journal\":{\"name\":\"The 2nd International Electronic Conference on Biomedicines\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"The 2nd International Electronic Conference on Biomedicines\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.3390/ecb2023-14086\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"The 2nd International Electronic Conference on Biomedicines","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.3390/ecb2023-14086","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Nepeta nuda L. Plant Extract Preserves the Morphology of Red Blood Cells Subjected to Oxidative Stress
.net/. Abstract: We show that an extract from catmint ( Nepeta nuda L.) flowers is not hemotoxic and does not alter erythrocytes’ morphology. H 2 O 2 -induced oxidative stress leads to an increase in lipid peroxidation, accompanied by a reduction in the number of biconcave cells and an increase in the number of echinocytes. Pre-treatment of erythrocytes with this extract does not reduce the lipid peroxidation level; however, it results in partial restoration of the relative abundance of biconcave cells and a respective reduction in the echinocytes’ quantity. Our data reveal the concentrations at which the examined extract exhibits a protective effect on erythrocytes’ morphology under the condition of H 2 O 2 -induced oxidative stress.