酒精与儿童:临床和法医研究

S. C. Plis, L.A. Kovalenko, O. V. Veselkina, D. M. Dolginov, Y. N. Ostapenko, Vasily V. Vlassov, V. A. Klevno
{"title":"酒精与儿童:临床和法医研究","authors":"S. C. Plis, L.A. Kovalenko, O. V. Veselkina, D. M. Dolginov, Y. N. Ostapenko, Vasily V. Vlassov, V. A. Klevno","doi":"10.17816/fm709","DOIUrl":null,"url":null,"abstract":"Background. The study aimed to evaluate the differences in the clinical pictures in the group of alcohol intoxication (without the loss of conscious) and alcohol poisoning (with the loss of conscious). \nAims. The study aimed to establish what levels of ethanol in the blood in children and adolescents lead to the loss of consciousness, and thus, ethanol poisoning. \nMaterials and Methods. Based on the obtained data on underage children (forensic bureau, pediatric hospital No. 13, Moscow), the patients were divided into two groups: (1) children who had mild or significant disorders after alcohol consumption (alcohol intoxication) and (2) children who faced coma, respiratory arrest, or death after alcohol consumption (alcohol poisoning). Group 1 included 49 cases of hospitalization of children aged 12-17 years old to the Toxicological Unit. Group 2 included 18 children aged 11-17 years old. \nResults. The levels of ethanol in the blood and urine of males and in the blood of females were significantly higher than in patients with alcohol intoxication. The objective status of patients was the same. There were no differences in alcohol pharmacokinetics (resorption, elimination). There were no differences in the instrumental parameter readings either. In the present study, alcohol intoxication and alcohol poisoning were not associated with dangerous changes in such parameters as SBP, DBP, HR, and RR. \nConclusion. The results showed that ethanol poisoning in children aged 11-17 years old developed at the concentration of ethanol 2.61 g/L in the blood and 3.01 g/L in the urine. Besides, there were no significant differences in the instrumental parameters.","PeriodicalId":346404,"journal":{"name":"Russian Journal of Forensic Medicine","volume":"1 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2022-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Alcohol and children: clinical and forensic study\",\"authors\":\"S. C. Plis, L.A. Kovalenko, O. V. Veselkina, D. M. Dolginov, Y. N. Ostapenko, Vasily V. Vlassov, V. A. Klevno\",\"doi\":\"10.17816/fm709\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Background. The study aimed to evaluate the differences in the clinical pictures in the group of alcohol intoxication (without the loss of conscious) and alcohol poisoning (with the loss of conscious). \\nAims. The study aimed to establish what levels of ethanol in the blood in children and adolescents lead to the loss of consciousness, and thus, ethanol poisoning. \\nMaterials and Methods. Based on the obtained data on underage children (forensic bureau, pediatric hospital No. 13, Moscow), the patients were divided into two groups: (1) children who had mild or significant disorders after alcohol consumption (alcohol intoxication) and (2) children who faced coma, respiratory arrest, or death after alcohol consumption (alcohol poisoning). Group 1 included 49 cases of hospitalization of children aged 12-17 years old to the Toxicological Unit. Group 2 included 18 children aged 11-17 years old. \\nResults. The levels of ethanol in the blood and urine of males and in the blood of females were significantly higher than in patients with alcohol intoxication. The objective status of patients was the same. There were no differences in alcohol pharmacokinetics (resorption, elimination). There were no differences in the instrumental parameter readings either. In the present study, alcohol intoxication and alcohol poisoning were not associated with dangerous changes in such parameters as SBP, DBP, HR, and RR. \\nConclusion. The results showed that ethanol poisoning in children aged 11-17 years old developed at the concentration of ethanol 2.61 g/L in the blood and 3.01 g/L in the urine. Besides, there were no significant differences in the instrumental parameters.\",\"PeriodicalId\":346404,\"journal\":{\"name\":\"Russian Journal of Forensic Medicine\",\"volume\":\"1 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-08-26\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Russian Journal of Forensic Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.17816/fm709\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Russian Journal of Forensic Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.17816/fm709","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

摘要

背景。本研究旨在评价酒精中毒(无意识丧失)组与酒精中毒(有意识丧失)组临床表现的差异。目标这项研究旨在确定儿童和青少年血液中的乙醇含量会导致意识丧失,从而导致乙醇中毒。材料与方法。根据获得的未成年儿童数据(莫斯科第13儿科医院法医局),将患者分为两组:(1)饮酒后出现轻度或严重障碍的儿童(酒精中毒)和(2)饮酒后出现昏迷、呼吸停止或死亡的儿童(酒精中毒)。第1组包括49例12-17岁儿童在毒理学部门住院。第二组18例,年龄11-17岁。结果。男性和女性的血液和尿液中的乙醇含量明显高于酒精中毒患者。患者的客观状态相同。两组在酒精药代动力学(吸收、消除)方面无差异。仪器参数读数也无差异。在本研究中,酒精中毒和酒精中毒与收缩压、舒张压、HR和RR等参数的危险变化无关。结论。结果表明,11-17岁儿童乙醇中毒发生在乙醇血浓度为2.61 g/L、尿浓度为3.01 g/L时。此外,在仪器参数上也没有显著差异。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Alcohol and children: clinical and forensic study
Background. The study aimed to evaluate the differences in the clinical pictures in the group of alcohol intoxication (without the loss of conscious) and alcohol poisoning (with the loss of conscious). Aims. The study aimed to establish what levels of ethanol in the blood in children and adolescents lead to the loss of consciousness, and thus, ethanol poisoning. Materials and Methods. Based on the obtained data on underage children (forensic bureau, pediatric hospital No. 13, Moscow), the patients were divided into two groups: (1) children who had mild or significant disorders after alcohol consumption (alcohol intoxication) and (2) children who faced coma, respiratory arrest, or death after alcohol consumption (alcohol poisoning). Group 1 included 49 cases of hospitalization of children aged 12-17 years old to the Toxicological Unit. Group 2 included 18 children aged 11-17 years old. Results. The levels of ethanol in the blood and urine of males and in the blood of females were significantly higher than in patients with alcohol intoxication. The objective status of patients was the same. There were no differences in alcohol pharmacokinetics (resorption, elimination). There were no differences in the instrumental parameter readings either. In the present study, alcohol intoxication and alcohol poisoning were not associated with dangerous changes in such parameters as SBP, DBP, HR, and RR. Conclusion. The results showed that ethanol poisoning in children aged 11-17 years old developed at the concentration of ethanol 2.61 g/L in the blood and 3.01 g/L in the urine. Besides, there were no significant differences in the instrumental parameters.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信