肠内营养;简单的?我们能实现这个目标吗?

P. Tasar, H. Turkan, Z. Gezer, D. Kerimoglu, A. Koç, S. Kılıçturgay
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摘要

目的:肠内营养(EN)是功能性胃肠道患者安全、耐受性良好、有效的营养支持。EN的主要问题是营养产品的不耐受和达到目标剂量的问题。这是一项前瞻性观察性研究,调查在我们的住院诊所和重症监护病房接受EN治疗的患者的营养相关问题,这些问题的解决方案以及达到目标剂量的时间。方法:本前瞻性研究于2015年11月1日- 2016年11月1日进行。本研究评估了患者的人口统计学发现、营养状况、每日计算卡路里(25千卡/千克/天)、每日计算蛋白质剂量(1.5克/千克/天)、每日输送卡路里、每日输送蛋白质剂量、是否应用额外的肠外营养、生化参数(血糖、Na、K、Ca、Mg、胆固醇、肝功能检查、尿素、CRP、白蛋白、白蛋白前)、不耐受问题、并发症和EN终止原因。结果:本期住院患者2258例,共70例(3.1%)采用EN(女/男:30/40,平均年龄60±16.5岁)。平均申请时间为11.5(2-42)天。其中26例患者NRS-2002评分≥3分,仅有6例患者BMI<18.8。热量和蛋白质的施用量分别低于计算值的37.14%和52.8%。40.54%的恶性肿瘤患者接受免疫营养治疗。20例患者存在胃肠道相关问题。腹泻是肠内支持过程中最重要的问题。20%的人群存在口服补充剂不耐受问题。35.7%的患者检测到高血糖,其中一半以上的患者血糖水平在200-300 mg/dL之间。近53%的患者为恶性肿瘤,但出院时仅有5例患者有口服补充处方。结论:恶性肿瘤患者的免疫营养方案没有得到很好的遵守,且患者出院后很少给予口服补充处方,且热量和蛋白质摄入不准确。此外,产品不耐受严重频繁,应更积极地改变产品和剂量。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Enteral nutrition; uncomplicated? Can we achieve the target?
Objective: Enteral nutrition (EN) is safe, well tolerated and efficient nutritional support for patients with functional gastrointestinal (GI) tract. The major problems of EN are intolerance of the nutrition products and problems of achieving the targeted dose. This is a prospective observational study investigating the nutrition related problems, solutions to those problems, and the time for achieving the targeted dose in patients who received EN in our inpatient clinic and intensive care unit. Methods: This prospective study was made between 11/01/2015-11/01/2016. This study evaluated patients demographic findings, nutrition status, daily calculated calories (25 kcal/kg/day), daily calculated protein dose (1.5 gr/kg/day), daily delivered calories, daily delivered protein dose, whether or not additional parenteral nutrition applied, biochemical parameters (blood sugar, Na, K, Ca, Mg, cholesterol, liver function tests, urea, CRP, albumin, prealbumin), intolerance issues, complications and EN termination reasons. Results: Considering 2258 patients hospitalized during this period, a total of 70 patients (3.1%) were applied EN (Female/Male: 30/40, The mean age of the patients was 60±16.5 years). The average application time is 11.5 (2-42) days. Among these patients, 26 had an NRS-2002 score ≥3, and only 6 had a BMI<18.8. The rate of calorie and protein application was lower than the calculated, respectively, 37.14% and 52.8% of the cases. It was observed that 40.54% of total malignant patients were subjected to immunonutrition. There were GI tract related problems in 20 patients. Diarrhea was the most important problem during enteral support. Oral supplementation intolerance problem was observed in 20% of the population. Hyperglycemia was detected in 35.7% of the patients, and more than half of them were between 200-300 mg/dL levels. Almost 53% of the patients had malignancy, however, only 5 of them had prescription for oral supplementation during discharge. Conclusion: EN was performed less than required with inaccurate calories and protein intake, and immunonutrition protocols in malignant patients are not properly complied and oral supplement prescription for those patients is rarely given after hospital discharge. Additionally, product intolerance is seriously frequent, and product and dosage changes should be done more actively.
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