个性化医疗的实用工具

Chetana Gavankar, Aditya Phatak, N. Thakkar, Vaidehi Patel, Bhoomi Pragda, Rutuja Lathkar
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引用次数: 1

摘要

生物医学研究淹没在数据中,却渴求知识。随着科学文献数量的空前增长,需要革命性的数据管理措施。从这些文本数据中获取、分析和挖掘知识已成为一项非常重要的任务。其中一个来源是NCBI,它拥有一系列与生物技术和生物医学相关的数据库(PubMed)。它是生物信息学工具和服务的重要资源。根据生物信息学家的需要,提出了一个包含PubMed中所有生物医学文献的系统。该工具使用机器学习和自然语言处理,旨在帮助临床医生和生物医学研究人员理解并以图形方式表示特定疾病背景下基因的相关性。它还将支持针对特定实体的生物管理搜索,以获得针对特定疾病的最有效药物列表。该系统是通过使用标准的信息检索措施,即精度,召回和f得分来衡量搜索结果的相关性进行评估。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Utility Tool for Personalised Medicine
Biomedical research is drowning in data, yet starving for knowledge. As the volume of scientific literature is growing unprecedentedly, revolutionary measures are needed for data management. Accessibility, analysis and mining knowledge from this textual data has become a very important task. One such source is NCBI that houses a series of databases (PubMed) relevant to biotechnology and bio-medicine. It is an important resource for bioinformatics tools and services. In this paper, a system is proposed that encases all the biomedical articles of PubMed as needed by bioinformaticians. Using machine learning and natural language processing, the tool aims at assisting clinicians and biomedical researchers to understand and graphically represent the relevance of gene in a given disease context. It will also support entity-specific bio-curation searches to get a list of most effective drugs for a particular disease. The system is evaluated by using standard information retrieval measures namely, Precision, Recall and F-score to measure the relevance of search results.
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