部分药用植物粗提物的植物化学分析及抗微生物和抗氧化活性。

Sandipty Kayastha, Mitesh Shrestha, H. K. Chaudhary, K. Shrestha, K. Manandhar, B. Poudel
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引用次数: 0

摘要

背景:寻找潜在的天然生物活性化合物已经进行了很长时间。在天然产物化学领域工作的研究人员开始意识到民族医药知识的重要性。方法:本研究的目的是对不同植物进行初步分析,以了解其治疗潜力。为此,从四种不同的植物标本中制备甲醇提取物。对不同浓度的提取物进行了抗微生物、抗氧化和细胞毒性试验。结果:甲醇浸提法提取无尾草的提取率最高。植物化学分析检测到这些物种存在不同类型的次生代谢物。在抗氧化活性和细胞毒性试验中,榕树的酚类和黄酮类含量最高,IC50和LC50最低。结论:所选植物可能具有较强的治疗作用,可进一步进行生物活性化合物的分离鉴定。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Phytochemical Analysis, Antimicrobial and Antioxidant Activity of Crude Extracts from Selected Medicinal Plants.
Background: The search for potential natural bioactive compounds has been carried out for a long time.  Researchers working in the field of natural product chemistry are starting to realize the importance of  ethnomedicinal knowledge. Methodology: The aim of this study was to carry out preliminary analysis of different plants to understand their  therapeutic potential.To this end, methanolic extracts were prepared from four different plant specimens.  ntimicrobial, antioxidant and cytotoxicity assays were carried out at different concentrations of the extracts. Results: The highest percentage yield by methanol extraction was achieved from Sapindus murokosii.  Phytochemical analysis detected presence of different types of secondary metabolites present in these species.  Among the plants selected, Ficus religiosa showed the highest quantity of phenolics and flavonoids content  along with lowest IC50 and LC50 for anti-oxidant activity and cytotoxicity assay respectively.  Conclusion: The results obtained leads to the conclusion that the selected plants might be possessing strong  therapeutics which can be further analyzed for isolation and identification of bioactive compounds.
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