JM Nieto Villar, A. Guerra, D. J. Rodriguez, E. Silva, J. Mar, G. Cocho, R. Mansilla
{"title":"癌症的慢性疗法：上皮-间质转化","authors":"JM Nieto Villar, A. Guerra, D. J. Rodriguez, E. Silva, J. Mar, G. Cocho, R. Mansilla","doi":"10.15406/mojgg.2019.04.00192","DOIUrl":null,"url":null,"abstract":"The epithelial-mesenchymal transition (EMT) plays a fundamental role in embryonic development and metastasis.4 The metastasis of cancer is not only the most fatal stage but also the most complex one.5 During this process cell-cell interaction and cell-membrane basal interaction is lost, this implies losing the polarity and the typical forms of the epithelial phenotypes, which occurs through genotypic changes.6 The cells acquire then a Mesenchymal phenotype characterized by a high capacity for invasion and resistance to apoptosis.7","PeriodicalId":163225,"journal":{"name":"MOJ Gerontology & Geriatrics","volume":"1 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2019-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"4","resultStr":"{\"title\":\"Chronotherapy of cancer: epithelial-mesenchymal transition\",\"authors\":\"JM Nieto Villar, A. Guerra, D. J. Rodriguez, E. Silva, J. Mar, G. Cocho, R. Mansilla\",\"doi\":\"10.15406/mojgg.2019.04.00192\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The epithelial-mesenchymal transition (EMT) plays a fundamental role in embryonic development and metastasis.4 The metastasis of cancer is not only the most fatal stage but also the most complex one.5 During this process cell-cell interaction and cell-membrane basal interaction is lost, this implies losing the polarity and the typical forms of the epithelial phenotypes, which occurs through genotypic changes.6 The cells acquire then a Mesenchymal phenotype characterized by a high capacity for invasion and resistance to apoptosis.7\",\"PeriodicalId\":163225,\"journal\":{\"name\":\"MOJ Gerontology & Geriatrics\",\"volume\":\"1 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-07-26\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"4\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"MOJ Gerontology & Geriatrics\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.15406/mojgg.2019.04.00192\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"MOJ Gerontology & Geriatrics","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15406/mojgg.2019.04.00192","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Chronotherapy of cancer: epithelial-mesenchymal transition
The epithelial-mesenchymal transition (EMT) plays a fundamental role in embryonic development and metastasis.4 The metastasis of cancer is not only the most fatal stage but also the most complex one.5 During this process cell-cell interaction and cell-membrane basal interaction is lost, this implies losing the polarity and the typical forms of the epithelial phenotypes, which occurs through genotypic changes.6 The cells acquire then a Mesenchymal phenotype characterized by a high capacity for invasion and resistance to apoptosis.7
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
