{"title":"苋尾提取物对多重耐药鲍曼不动杆菌和肺炎克雷伯菌的抑菌活性研究","authors":"M. Bari, M. A. Alfaki","doi":"10.56936/10.56936/18290825-2023.17.2-118","DOIUrl":null,"url":null,"abstract":"Nowadays, new and effective antifungal or antimicrobial medications are required due to the rise of drug-resistant organisms. Most people have thought about using medicinal herbs to naturally treat illnesses with bacterial origins. In this study, two multidrug resistant (MDR) bacteria were used as in vitro models to compare the effects of antimicrobial medicinal plant extracts. The antibacterial effects of a Amaranthus caudatus seed extract was elicited by different solvents on Acinetobacter baumannii and Klebsiella pneumoniae were examined in this experimental study using the disc diffusion assay and the minimum inhibitory concentration (MIC) method. GC-MS analysis identified several antibacterial compounds, viz. hexadecane, dodecane, undecane, heptacosane, etc. The extracts’ effectiveness was examined through their anti-bacterial and anti-oxidant activity. Plant extracts with various compounds demonstrated antibacterial activity in the current study. They can therefore serve as a new source of antibacterial compounds.","PeriodicalId":151964,"journal":{"name":"NAMJ 17 (2023)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Antimicrobial activity of amaranthus caudatus extract against multidrug resistant acinetobacter baumannii and klebsiella pneumoniae\",\"authors\":\"M. Bari, M. A. Alfaki\",\"doi\":\"10.56936/10.56936/18290825-2023.17.2-118\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Nowadays, new and effective antifungal or antimicrobial medications are required due to the rise of drug-resistant organisms. Most people have thought about using medicinal herbs to naturally treat illnesses with bacterial origins. In this study, two multidrug resistant (MDR) bacteria were used as in vitro models to compare the effects of antimicrobial medicinal plant extracts. The antibacterial effects of a Amaranthus caudatus seed extract was elicited by different solvents on Acinetobacter baumannii and Klebsiella pneumoniae were examined in this experimental study using the disc diffusion assay and the minimum inhibitory concentration (MIC) method. GC-MS analysis identified several antibacterial compounds, viz. hexadecane, dodecane, undecane, heptacosane, etc. The extracts’ effectiveness was examined through their anti-bacterial and anti-oxidant activity. Plant extracts with various compounds demonstrated antibacterial activity in the current study. They can therefore serve as a new source of antibacterial compounds.\",\"PeriodicalId\":151964,\"journal\":{\"name\":\"NAMJ 17 (2023)\",\"volume\":\"1 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1900-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"NAMJ 17 (2023)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.56936/10.56936/18290825-2023.17.2-118\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"NAMJ 17 (2023)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.56936/10.56936/18290825-2023.17.2-118","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Antimicrobial activity of amaranthus caudatus extract against multidrug resistant acinetobacter baumannii and klebsiella pneumoniae
Nowadays, new and effective antifungal or antimicrobial medications are required due to the rise of drug-resistant organisms. Most people have thought about using medicinal herbs to naturally treat illnesses with bacterial origins. In this study, two multidrug resistant (MDR) bacteria were used as in vitro models to compare the effects of antimicrobial medicinal plant extracts. The antibacterial effects of a Amaranthus caudatus seed extract was elicited by different solvents on Acinetobacter baumannii and Klebsiella pneumoniae were examined in this experimental study using the disc diffusion assay and the minimum inhibitory concentration (MIC) method. GC-MS analysis identified several antibacterial compounds, viz. hexadecane, dodecane, undecane, heptacosane, etc. The extracts’ effectiveness was examined through their anti-bacterial and anti-oxidant activity. Plant extracts with various compounds demonstrated antibacterial activity in the current study. They can therefore serve as a new source of antibacterial compounds.