苋尾提取物对多重耐药鲍曼不动杆菌和肺炎克雷伯菌的抑菌活性研究

M. Bari, M. A. Alfaki
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引用次数: 0

摘要

如今,由于耐药生物的增加,需要新的和有效的抗真菌或抗微生物药物。大多数人都想过用草药自然地治疗由细菌引起的疾病。本研究以两种耐多药(MDR)细菌为体外模型,比较药用植物提取物的抗菌作用。采用圆盘扩散法和最小抑菌浓度(MIC)法,研究了不同溶剂条件下苋菜籽提取物对鲍曼不动杆菌和肺炎克雷伯菌的抑菌作用。GC-MS分析鉴定出几种抗菌化合物,分别为十六烷、十二烷、十一烷、七烷等。通过抗细菌和抗氧化活性来考察提取物的有效性。在目前的研究中,含有多种化合物的植物提取物显示出抗菌活性。因此,它们可以作为抗菌化合物的新来源。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Antimicrobial activity of amaranthus caudatus extract against multidrug resistant acinetobacter baumannii and klebsiella pneumoniae
Nowadays, new and effective antifungal or antimicrobial medications are required due to the rise of drug-resistant organisms. Most people have thought about using medicinal herbs to naturally treat illnesses with bacterial origins. In this study, two multidrug resistant (MDR) bacteria were used as in vitro models to compare the effects of antimicrobial medicinal plant extracts. The antibacterial effects of a Amaranthus caudatus seed extract was elicited by different solvents on Acinetobacter baumannii and Klebsiella pneumoniae were examined in this experimental study using the disc diffusion assay and the minimum inhibitory concentration (MIC) method. GC-MS analysis identified several antibacterial compounds, viz. hexadecane, dodecane, undecane, heptacosane, etc. The extracts’ effectiveness was examined through their anti-bacterial and anti-oxidant activity. Plant extracts with various compounds demonstrated antibacterial activity in the current study. They can therefore serve as a new source of antibacterial compounds.
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