妇女休息时呼吸系统指标的特点及其在下一支烟燃烧时的变化

T. Shevchuk, L. Aponchuk, V. S. Pikalyuk, O. O. Olishkevich
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引用次数: 0

摘要

现代社会面临的一个重要问题是,各种各样的上瘾的人越来越多,其中最常见的是吸烟。吸烟及其医学、人口学和经济后果是许多国内外科学家感兴趣的科学问题。这就是为什么这篇科学文章的目的是研究女性在休息和另一支香烟燃烧时呼吸系统状态的特点。这项研究是在乌克兰列西亚国立大学生物和林业学院人类和动物生理学系医学和生物监测及公共卫生实验室对60名17-21岁的妇女进行的。在研究的第一阶段,测量绝对人体测量指标,如身高、体重、胸围。在第二阶段,女性接受Fagerström测试的采访。根据其结果,该研究分为3组:第一组-有3年以上吸烟史,每天吸烟10支以上,高度依赖的妇女;第二组-有1-3年吸烟史,每天吸烟10支以上,具有中低程度依赖的妇女;第三组-(对照)不吸烟的妇女。研究的下一阶段包括使用功能气相摄影法(PTG)对女性在休息和吸烟15分钟后的外部呼吸系统进行功能诊断。相关指标的登记和分析使用诊断自动化复杂“Cardio+”。统计数据处理采用普遍接受的方差统计方法(因为结果的分布是正态的),使用MS Excel 2007软件。这篇文章介绍了一项研究,在休息时和燃烧另一支烟15分钟后的外部呼吸状态,揭示了吸烟对吸烟女性呼吸系统的负面影响。该研究可以对17-21岁吸烟女性的呼吸功能指标进行详细分析,并将其与不吸烟女性进行比较。根据所获得的结果,与女性对照组相比,女性吸烟者(I组和II组)在休息时和下一支烟点燃后15分钟的外呼吸容积(FVC、VC、FEV1)指标以及Tiffeneau-Pinelli检验均显著降低,p<0.05。对经支气管进入肺部的气流速度(呼气25%、50%、75%、PEF)的分析表明,实验组女性的MEF从25%逐渐下降到75%,但在第1组和第3组之间,仅在第2支烟燃烧后15分钟的75%水平上有显著下降(p<0.05)。II组和III组妇女在休息时和再次吸烟后15分钟计算的蒂菲内奥-皮内利指数(表征阻塞性呼吸衰竭的存在)的值有统计学上的显著差异。因此,这些指标的下降表明存在中、小支气管的支气管阻塞,以及呼吸肌力量和支气管通畅的破坏。研究还表明,在不吸烟的妇女组(对照)中,外部呼吸的体积和速度指标对香烟燃烧的反应性(降低)更高。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Peculiarities of indicators of the respiratory system in women at rest and their changes during the burning of the next cigarette
One of the important problems facing modern society is the increase in the number of people with various types of addictions, the most common of which is smoking. Smoking and its medical-demographic and economic consequences are in the circle of scientific interests of many domestic and foreign scientists. That is why the aim of the scientific article is to study the peculiarities of the state of the respiratory system in women at rest and during the burning of another cigarette. The study was conducted in the Laboratory of Medical and Biological Monitoring and Public Health at the Department of Human and Animal Physiology, Faculty of Biology and Forestry, Lesya Ukrainka Volyn National University for 60 women aged 17-21. At the first stage of the study, absolute anthropometric indicators were measured, such as height, weight, chest circumference. In the second stage women were interviewed on the Fagerström test. According to its results, the study is divided into 3 groups: Group I – women who have a history of smoking more than 3 years, burn more than 10 cigarettes per day and have a high level of dependence, Group II – women who have a history of smoking 1-3 years, up to 10 cigarettes are smoked per day and have a low and medium level of dependence, Group III – (control) women who do not smoke. The next stage of the study involved a functional diagnosis of the external respiratory system in women at rest and 15 minutes after smoking a cigarette using the functional method of pneumotachography (PTG). Registration and analysis of relevant indicators was carried out using a diagnostic automated complex “Cardio+”. Statistical data processing was performed using generally accepted methods of variation statistics (because the distribution of the results was normal) using MS Excel 2007 software. This article presents a study of the state of external respiration at rest and 15 minutes after burning another cigarette, which revealed the negative effects of smoking on the respiratory system of women who smoke. The study made it possible to make a detailed analysis of indicators of respiratory function in women aged 17-21 years, smokers and compare them with non-smokers. Based on the obtained results, it was found that in women smokers (groups I and II) there is a significant decrease in volume (FVC, VC, FEV1) indicators of external respiration, as well as the Tiffeneau-Pinelli test at p<0.05, compared with the group of women control group both at rest and 15 minutes after firing the next cigarette. Analysis of velocity (MEF at the level of exhalation 25 %, 50 %, 75 %, PEF) of airflow through the bronchi to the lungs indicates a gradual decrease from MEF 25 % to MEF 75 % in women of the experimental groups, but a significant decrease is observed only at the level sight of 75 % in 15 min after burning of the next cigarette between I and III groups (at p<0.05). A statistically significant difference between the values of the calculated Tiffeneau-Pinelli index, which characterizes the presence of obstructive respiratory failure, in women of groups II and III both at rest and 15 minutes after burning another cigarette. Thus, a decrease in these indicators indicates the presence of bronchial obstruction of the middle and small bronchi, as well as a violation of respiratory muscle strength and bronchial patency. It has also been shown that the reactivity (reduction) of volumetric and velocity indicators of external respiration to cigarette burning was higher in the group of women who do not smoke (control).
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