利用强度持续时间曲线研究下运动神经元损伤引起的肌肉异常收缩:初步研究

Anil Kumar, Seema Singh, Ashok Sharma
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引用次数: 0

摘要

由脑干和脊髓的下运动神经元损伤引起的症状被称为“下运动神经元综合征”。对下部运动神经元细胞体或其外周轴突的损伤导致受影响肌肉的瘫痪(运动丧失)或麻痹(无力)。除了瘫痪和/或瘫瘫,下运动神经元综合征还包括由于感觉运动反射弧的传出肢体(运动肢体)中断而导致反射丧失(反射反射)。目的利用SD曲线研究神经失用症患者LMN(下运动神经元)损伤引起的肌肉异常收缩。目的是寻找无患侧的流变酶值和Chronaxie值,并与患者患侧进行比较,并在患侧图中识别扭结(如果存在)。对6例神经受压患者进行了纵向研究。采集双肢样本,测量股四头肌、胫骨前肌和三角肌区域的流变酶和Chronaxie。受试者接受诊断性电刺激(电流),产生脉冲持续时间从0.01到300毫秒不等的方波。电刺激采用恒流型。应用标准差和T检验得到的结果显示,影响侧的Chronaxie值发生了显著变化。得到P值(P≤0.04)。SD曲线出现扭结表明患者患侧退行性变的反应。研究表明,患者的肌肉兴奋和收缩能力不成比例。对下部运动神经元的损伤也会导致肌肉张力的丧失。所涉及的肌肉也可能表现为纤颤和束状,这分别是单个失神经肌纤维或运动单元的自发抽搐特征。Anil Kumar, Seema Singh, Ashok Kumar Sharma Era's勒克瑙医学院和医院生理学系,物理治疗系,萨法拉兹干,勒克瑙,upp,印度226003 Era's医学研究杂志:借助力量持续时间曲线研究下运动神经元病变引起的肌肉异常收缩:一项初步研究VOL.6 NO.1原创文章页:时代医学研究杂志第6卷第1期Seema Singh博士勒克瑙医学院生理学系,勒克瑙-226003电子邮件:singh_seema2007@yahoo.com联系电话:+91-9451993425通讯地址收稿日期:08-10-2018收稿日期:27-06-2019
本文章由计算机程序翻译,如有差异,请以英文原文为准。
TO STUDY THE ABNORMAL MUSCLE CONTRACTION DUE TO LOWER MOTOR NEURON LESION WITH THE HELP OF STRENGTH DURATION CURVE: A PILOT STUDY
The symptoms that arise from damage to the lower motor neurons of the brainstem and spinal cordare referred to as the “lower motor neuron syndrome.” Damage to lower motor neuron cell bodies or their peripheral axons results in paralysis (loss of movement) or paresis (weakness) of the affected muscles. In addition to paralysis and/or paresis, the lower motor neuron syndrome includes a loss of reflexes (areflexia) due to interruption of the efferent (motor) limb of the sensory motor reflex arcs. Aim was to study the abnormal muscle contraction due to LMN (lower motor neuron) lesion with the help of SD curve patient suffering from Neurapraxia. Objectives was to find Rheobase and Chronaxie values in non-effected side and compare it with effected side of the Patient and identification of kink (if present) in the graph of effected side. A longitudinal study was done on 6 subjects suffering from nerve compression. Sample was collected from bilateral limb Rheobase and Chronaxie were measured at the regions of the Quadriceps, Tibialis Anterior and Deltoid muscle. Subject gone through diagnostic Electrical Stimulation (galvanic current) which produce square wave of various pulse duration ranging from 0.01 to 300 msec. Electrical stimulation used was of constant current type. Result were obtained by applying standard deviation and T test, there is a significant change in the value of Chronaxie in the effected side. P value obtained (p ≤ 0.04). Presence of kink in the SD curve shows the reaction of degeneration in the effected side of the patients. Study showed that the patients suffer from disproportionate muscle excitation and contraction ability. Damage to lower motor neurons also entails a loss of muscle tone, since tone. The muscles involved may also exhibit fibrillations and fasciculation, which are spontaneous twitches characteristic of single denervated muscle fibers or motor units, respectively. Anil Kumar, Seema Singh, Ashok Kumar Sharma Department of Physiology, Department of Physiotherapy Era's Lucknow Medical College & Hospital, Sarfarazganj Lucknow, U.P., India-226003 ERA’S JOURNAL OF MEDICAL RESEARCH TO STUDY THE ABNORMAL MUSCLE CONTRACTION DUE TO LOWER MOTOR NEURON LESION WITH THE HELP OF STRENGTH DURATION CURVE: A PILOT STUDY VOL.6 NO.1 Original Article Page: 49 ERA’S JOURNAL OF MEDICAL RESEARCH, VOL.6 NO.1 Dr. Seema Singh Department of Physiology Era’s Lucknow Medical College & Hospital, Lucknow-226003 Email: singh_seema2007@yahoo.com Contact no:+91-9451993425 Address for correspondence Received on : 08-10-2018 Accepted on : 27-06-2019
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