Valentina Arsenijevic-Arsic, N. Arsovic, M. Dzamic, A. Trpković, Ivana Zec-Kranjcic, V. Djukic
{"title":"免疫正常耳真菌病患者假丝酵母菌的蛋白酶活性","authors":"Valentina Arsenijevic-Arsic, N. Arsovic, M. Dzamic, A. Trpković, Ivana Zec-Kranjcic, V. Djukic","doi":"10.2298/JMH0402171A","DOIUrl":null,"url":null,"abstract":"Summary: Otomycosis is a fungal infection of the ear dominantly caused by Candida and Aspergillus spp. The possible virulence factors of Candida spp. are enzymes, such as proteases, phospholipases, phosphatases and esterase. Protease production in Candida strains isolated from patients with otomycosis is, according to our knowledge, not investigated. The present study was aimed at determining in vitro protease activity in 28 strains of Candida spp. (C. parapsilosis, C. famata, C. guilliermondii, C. albicans and C. kefyr) isolated from patients with otomycosis. The majority of isolated strains 25/28 (89.28%) were protease positive. The protease Pz ranged from 0.691 to 0.851. The futher investigation is necessary to clarify contribution of protease production to Candida virulence associated with otomycosis.","PeriodicalId":287983,"journal":{"name":"Jugoslovenska Medicinska Biohemija-yugoslav Medical Biochemistry","volume":"1 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"5","resultStr":"{\"title\":\"Protease activities of Candida spp. isolated from immunocompetent patients with otomycosis\",\"authors\":\"Valentina Arsenijevic-Arsic, N. Arsovic, M. Dzamic, A. Trpković, Ivana Zec-Kranjcic, V. Djukic\",\"doi\":\"10.2298/JMH0402171A\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Summary: Otomycosis is a fungal infection of the ear dominantly caused by Candida and Aspergillus spp. The possible virulence factors of Candida spp. are enzymes, such as proteases, phospholipases, phosphatases and esterase. Protease production in Candida strains isolated from patients with otomycosis is, according to our knowledge, not investigated. The present study was aimed at determining in vitro protease activity in 28 strains of Candida spp. (C. parapsilosis, C. famata, C. guilliermondii, C. albicans and C. kefyr) isolated from patients with otomycosis. The majority of isolated strains 25/28 (89.28%) were protease positive. The protease Pz ranged from 0.691 to 0.851. The futher investigation is necessary to clarify contribution of protease production to Candida virulence associated with otomycosis.\",\"PeriodicalId\":287983,\"journal\":{\"name\":\"Jugoslovenska Medicinska Biohemija-yugoslav Medical Biochemistry\",\"volume\":\"1 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"1900-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"5\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Jugoslovenska Medicinska Biohemija-yugoslav Medical Biochemistry\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.2298/JMH0402171A\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Jugoslovenska Medicinska Biohemija-yugoslav Medical Biochemistry","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2298/JMH0402171A","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 5
摘要
摘要:耳真菌病是一种以念珠菌和曲霉菌为主的耳真菌感染，念珠菌的致毒因子可能是酶，如蛋白酶、磷脂酶、磷酸酶和酯酶。据我们所知，从耳真菌病患者中分离的念珠菌菌株的蛋白酶生产尚未进行调查。本研究旨在测定从耳真菌病患者分离的28株假丝酵母菌(C. parapsilosis, C. famata, C. guilliermondii, C. albicans和C. kefyr)的体外蛋白酶活性。分离菌株25/28(89.28%)蛋白酶阳性。蛋白酶Pz取值范围为0.691 ~ 0.851。进一步的研究是必要的，以阐明蛋白酶的生产贡献念珠菌毒力相关的耳霉菌病。
Protease activities of Candida spp. isolated from immunocompetent patients with otomycosis
Summary: Otomycosis is a fungal infection of the ear dominantly caused by Candida and Aspergillus spp. The possible virulence factors of Candida spp. are enzymes, such as proteases, phospholipases, phosphatases and esterase. Protease production in Candida strains isolated from patients with otomycosis is, according to our knowledge, not investigated. The present study was aimed at determining in vitro protease activity in 28 strains of Candida spp. (C. parapsilosis, C. famata, C. guilliermondii, C. albicans and C. kefyr) isolated from patients with otomycosis. The majority of isolated strains 25/28 (89.28%) were protease positive. The protease Pz ranged from 0.691 to 0.851. The futher investigation is necessary to clarify contribution of protease production to Candida virulence associated with otomycosis.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
