Aktivitas Antibakteri Ekstrak Etanol Daun Jambu Putih (Syzygium malaccense (L.) Merr. & L.M. Perry) Terhadap Pertumbuhan Escherichia coli dan Streptococcus mutans

ABSTRACT The content of flavonoids, saponins and other compounds in white guava leaves (Syzygium malaccense(L.) Merr. & L.M. Perry) is quite high and has the potential to be used as an antibacterial. The purpose of this study was to analyze the antibacterial effectiveness of guava leaf extract against the growth of Escherichia Coli and Streptococcus Mutans. White guava leaves (Syzygium malaccense(L.) Merr. & L.M. Perry) were macerated with 96% ethanol. The test method used agar diffusion with 5 groups, namely negative control Na.CMC, concentrations of 2%, 4%, and 6%, and positive control Ciprofloxacin. The samples used were Escherichia Coli and Streptococcus Mutans. The inhibition obtained against Escherichia Coli at a concentration of 2% was 12.3 mm, the concentration of 4% was 14.3 mm, the concentration of 6% was 18.67 mm, while the positive control was 23 mm and the negative control was with Na.CMC no visible obstacle zone. While the results obtained by Streptococcus Mutans at a concentration of 2% was 8.67 mm, the concentration of 4% was 11.67 mm, the concentration of 6% was 16.3 mm, while the positive control was 31 mm and the negative control did not show any inhibition areas. so it can be concluded that Guava Leaf Extract (Syzygium malaccense(L.) Merr. & LM Perry) at concentrations of 2%, 4%, 6% had activity against the growth of Escherichia Coli and Streptococcus Mutans (p < 0.005) but its effectiveness was still below Ciprofloxacin. (p < 0.005)