Hanat S. Mohamud, E. Alghamdi, A. Alhetheel, F. Almajid, A. Ahmed, A. Somily, D. Mohamed
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引用次数: 0
摘要
背景:HTLV献血者筛查是高流行国家推荐的做法。然而,尽管对沙特阿拉伯HTLV血清流行率的研究表明,这些病毒在该国的威胁有限,但对所有潜在献血者候选人进行HTLV- i /-II血清学筛查是强制性做法。自10年前沙特阿拉伯最后一次公布HTLV血清患病率以来,我们回顾了2014-2015年在利雅得哈立德国王大学医院(KKUH)就诊的23,668名献血者的数据,以确定这一强制性做法是否需要审查。材料和方法:在Abbott Architect系统上运行rHTLV检测进行血清学筛选。重复反应结果经Western Blot分析证实。结果:这项研究显示,在研究期间,23,668名献血者的HTLV-I/-II血清阳性率为零。讨论:我们进一步支持沙特阿拉伯作为HTLV非流行地区,并审查更具成本效益的战略,以尽量减少HTLV风险,作为强制性献血者筛查的替代方案。
Mandatory Blood Donor Screening for Human T-Cell Lymphotropic Virus Type I and Type II in Saudi Arabia: Need for Review
Background: HTLV blood donor screening is recommended practice in high prevalence countries. However, although studies of HTLV seroprevalence in Saudi Arabia agree these viruses present limited threat in the country, serological screening of HTLV-I/-II in all prospective blood donor candidates is mandatory practice. Since the last publication of HTLV seroprevalence in Saudi Arabia 10 years ago, we review 2014-2015 data of 23,668 blood donors attending King Khalid University Hospital (KKUH) Riyadh, to determine whether this mandatory practice needs review. Materials and methods:Serology screening was performed on the Abbott Architect system running the rHTLV assay. Repeat reactive results were confirmed by Western Blot analysis. Results: This study revealed zero HTLV-I/-II seroprevalence amongst 23,668 donors over the study period. Discussion: We further support Saudi Arabia as a HTLV non-endemic region, and review more cost-effective strategies to minimize HTLV risks as an alternative to mandatory blood donor screening.