EXPERIMENTAL STUDIES ON THE INFLUENCE OF VAGUS NERVE ON THE GASTRIC MOTILITY ESPECIALLY ON THE SIGNIFICANCE OF SELECTIVE VAGOTOMY AND SELECTIVE PROXIMAL VAGOTOMY

Eighteen dogs were used for experiments. Electodes were implanted on the stomach after selective vagotomy, selective proximal vagotomy, selective vagotomy with pyloroplasty and laparotomy (control) and electromyograms were recorded until a month after the implantation. Thirty dogs were exmained their gastric motility by means of strain gage meth od under the stimulation of various branches of vagus nerve by square pulses.Results were:1) Both vagotomized dogs showed remarkable increase of anti-peristaltic electrical discharges. In contrast there was no remarkable change on the normo peristaltic discharges.2) On the selectively vagotomized dogs both peristaltic electrical discharges descreased in height contrary to normals.3) After solid diet or hot milk, difference of patterns of normo peristaltic frequency between normal and selectively vagotomized dogs became remarkable. And its pattern in selective proximally vagotomized dogs was resemble to normals'.4) According to results of the stimulation with block or various sections of nerves it is considered that the antral branch of vagus nerve controls also motility of lower corpus. The propagation was very quick differing from anti-peristalsis. And it was considered to be cholinergic.5) By the stimulation of pyloric branch anti-peristalsis was scarcely occured. The pyloroplasty combined with selective vagotomy was not effective to decrease anti-peristaltic discharges after solid diet.