Utilization of Natural Ingredients Red Betel (Piper Crocatum) Extract and White Galangal (Alpinia Galanga) Extract as Raw Ingredients Hand Sanitizer (Research Phase I)

. WHO will announce the end of the Covid-19 pandemic, but the use of hand sanitizer is likely to become a positive new habit. Frequent use of hand sanitizers can cause effects, including dry hands, and even some people experience allergies to the skin of their hands due to the high alcohol content. It is necessary to look for alternative natural ingredients that do not have side effects but still have effective benefits. The research method begins with the manufacture of ethanol extract and aqueous extract of Piper crocatum and Alpinia galanga. All extracts were made into 5%, 10%, 15%, 25%, and 50% and then into a liquid soaking carp meat pieces that had been put into a test tube. Positive control used alcohol and sterile aqua. The ethanol extract of Piper crocatum 50% and 25% and the ethanol extract of Alpinia galanga 50% and 25% which had the best antimicrobial ability on day 19. The phytochemical test results showed that the ethanol extract of Piper crocatum contained alkaloids, tannins, steroids, and titerpenoids. Phytochemical test of ethanol extract of Alpinia galanga contained flavonoids, tannins, steroids, and titerpenoids. In conclusion, the ethanolic extract of Piper crocatum 50% and then 25% had the best antimicrobial ability, followed by the ethanolic extract of Alpinia galanga 50% and 25%. In the next stage, the best ethanol extract will be tested for microbes in a petri dish, before being used as a raw ingredient for hand sanitizer.