小舌长度对人咽模型气流和压力振荡的影响

Xuanming Zhao, Junshi Wang, Pan Han, J. Xi, Haibo Dong
{"title":"小舌长度对人咽模型气流和压力振荡的影响","authors":"Xuanming Zhao, Junshi Wang, Pan Han, J. Xi, Haibo Dong","doi":"10.1115/imece2019-11697","DOIUrl":null,"url":null,"abstract":"\n Unsteady uvula motions and the resultant pressure oscillations within the pharyngeal airway are critical for the pathology of snoring and sleeping apnea. In this paper, an immersed-boundary-method based direct numerical simulation flow solver was adopted to simulate the unsteady flows in an anatomically accurate pharynx model reconstructed from human magnetic resonance images (MRI) with prescribed uvula oscillation and airway obstruction. In order to study the influence of uvula length on the aerodynamics of pharyngeal airflow, simulations were conducted using various uvula models with scaled uvula lengths at 25%, 50%, 75%, and 100% of the original length, respectively. Analyses of vortex dynamics, pressure oscillations, and the aerodynamic force of uvula were conducted. It was found the length of uvula had significant impacts on vortex development as well as aerodynamic pressure/force. Shorter uvula induced weaker pressure oscillations and fewer vortices in the airway. Further fast Fourier transform analysis of pressures from different pressure probes showed higher-order harmonic waves other than the base frequency of uvula motion. This study is expected to bring understanding of snoring and sleep apnea and provide guidance for surgery.","PeriodicalId":332737,"journal":{"name":"Volume 3: Biomedical and Biotechnology Engineering","volume":"19 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2019-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Effect of Uvula Length on Airflow and Pressure Oscillation in a Human Pharynx Model\",\"authors\":\"Xuanming Zhao, Junshi Wang, Pan Han, J. Xi, Haibo Dong\",\"doi\":\"10.1115/imece2019-11697\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"\\n Unsteady uvula motions and the resultant pressure oscillations within the pharyngeal airway are critical for the pathology of snoring and sleeping apnea. In this paper, an immersed-boundary-method based direct numerical simulation flow solver was adopted to simulate the unsteady flows in an anatomically accurate pharynx model reconstructed from human magnetic resonance images (MRI) with prescribed uvula oscillation and airway obstruction. In order to study the influence of uvula length on the aerodynamics of pharyngeal airflow, simulations were conducted using various uvula models with scaled uvula lengths at 25%, 50%, 75%, and 100% of the original length, respectively. Analyses of vortex dynamics, pressure oscillations, and the aerodynamic force of uvula were conducted. It was found the length of uvula had significant impacts on vortex development as well as aerodynamic pressure/force. Shorter uvula induced weaker pressure oscillations and fewer vortices in the airway. Further fast Fourier transform analysis of pressures from different pressure probes showed higher-order harmonic waves other than the base frequency of uvula motion. This study is expected to bring understanding of snoring and sleep apnea and provide guidance for surgery.\",\"PeriodicalId\":332737,\"journal\":{\"name\":\"Volume 3: Biomedical and Biotechnology Engineering\",\"volume\":\"19 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-11-11\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Volume 3: Biomedical and Biotechnology Engineering\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1115/imece2019-11697\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Volume 3: Biomedical and Biotechnology Engineering","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1115/imece2019-11697","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1

摘要

不稳定的小舌运动和由此产生的压力振荡在咽气道内是关键的病理打鼾和睡眠呼吸暂停。本文采用基于浸入边界法的直接数值模拟流动求解器,模拟了由人体磁共振图像(MRI)重建的具有规定小舌振荡和气道阻塞的解剖精确咽部模型中的非定常流场。为了研究小舌长度对咽部气流空气动力学的影响,采用不同的小舌模型进行了模拟,小舌长度分别为原长度的25%、50%、75%和100%。对小舌的涡旋动力学、压力振荡和气动力进行了分析。研究发现,小舌长度对涡旋发展和气动压力/力有显著影响。小舌较短,气道内压力振荡较弱,旋涡较少。进一步对不同压力探头的压力进行快速傅里叶变换分析,发现小舌运动的基频以外的高次谐波。本研究旨在加深对打鼾和睡眠呼吸暂停的认识,并为手术提供指导。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effect of Uvula Length on Airflow and Pressure Oscillation in a Human Pharynx Model
Unsteady uvula motions and the resultant pressure oscillations within the pharyngeal airway are critical for the pathology of snoring and sleeping apnea. In this paper, an immersed-boundary-method based direct numerical simulation flow solver was adopted to simulate the unsteady flows in an anatomically accurate pharynx model reconstructed from human magnetic resonance images (MRI) with prescribed uvula oscillation and airway obstruction. In order to study the influence of uvula length on the aerodynamics of pharyngeal airflow, simulations were conducted using various uvula models with scaled uvula lengths at 25%, 50%, 75%, and 100% of the original length, respectively. Analyses of vortex dynamics, pressure oscillations, and the aerodynamic force of uvula were conducted. It was found the length of uvula had significant impacts on vortex development as well as aerodynamic pressure/force. Shorter uvula induced weaker pressure oscillations and fewer vortices in the airway. Further fast Fourier transform analysis of pressures from different pressure probes showed higher-order harmonic waves other than the base frequency of uvula motion. This study is expected to bring understanding of snoring and sleep apnea and provide guidance for surgery.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信