MSO神经细胞模型

Proceedings of the 1991 IEEE Seventeenth Annual Northeast Bioengineering Conference Pub Date : 1991-04-04 DOI:10.1109/NEBC.1991.154610

Y. Han, S. Colburn

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引用次数: 2

摘要

一个明确的模型，神经处理的个别细胞在内侧上橄榄(MSO)发展。它基于现有的生理数据，包括一个输入模式的描述性模型(表征AVCN中的浓密细胞)和一个明确的MSO细胞模型，该模型以膜电导和电位表达。该模型的公式允许对电导值和时间常数等参数选择的合理性进行评价。对于给定的一组参数，MSO细胞模型产生放电模式，并将这些模拟输出模式与生理学研究的实际模式进行比较。具体比较包括放电率、矢量强度和周期直方图。这些研究结果将为MSO神经元的双耳信号处理提供深入的见解，并为双耳心理物理学模型提供一个前沿。

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A neural cell model of MSO

An explicit model of neural processing for individual cells in the medial superior olive (MSO) is developed. It is based on available physiological data and consists of a descriptive model of input patterns (characterizing the bushy cells in the AVCN) and an explicit MSO cell model that is expressed in terms of membrane conductances and potentials. The formulation of this model permits the evaluation of the reasonableness of parameter choices such as conductance values and time constants. For a given set of parameters, the MSO cell model generates patterns of firing, and these simulated output patterns are compared to actual patterns from physiological studies. Specific comparisons include discharge rates, vector strengths, and period histograms. It is argued that the results of these studies will provide insights into the binaural signal processing in MSO neurons and will provide a front-end for models of binaural psychophysics.<>

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Proceedings of the 1991 IEEE Seventeenth Annual Northeast Bioengineering Conference

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