{"title":"小儿内脏利什曼病的严重形式-一个病例报告","authors":"Vardan Gevorgyan Nazeli, Valeri Apresyan Hripsime","doi":"10.23937/2643-461x/1710048","DOIUrl":null,"url":null,"abstract":"According to the World Health Organization, leishmaniasis is one of the seven most important tropical diseases, and it is a major global health concern. In Armenia, it is a re-emerging disease. We present a case of a one-year-old child from active visceral leishmaniasis (VL) focus with a history of intermittent fever and anemia, progressive weakness, abdominal distension with loss of appetite for 3 months. The case was confirmed as VL by a positive result for the rK39 test. Considering the symptoms and signs a combination of VL and secondary hemophagocytic lymphohistiocytosis (HLH) was suspected. The patient was treated with a 21 mg/kg total dose of AmBisome. The child responded positively to treatment, and HLH syndrome was excluded.","PeriodicalId":121181,"journal":{"name":"International Journal of Tropical Diseases","volume":"24 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2021-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A Severe Form of Pediatric Visceral Leishmaniasis - A Case Report\",\"authors\":\"Vardan Gevorgyan Nazeli, Valeri Apresyan Hripsime\",\"doi\":\"10.23937/2643-461x/1710048\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"According to the World Health Organization, leishmaniasis is one of the seven most important tropical diseases, and it is a major global health concern. In Armenia, it is a re-emerging disease. We present a case of a one-year-old child from active visceral leishmaniasis (VL) focus with a history of intermittent fever and anemia, progressive weakness, abdominal distension with loss of appetite for 3 months. The case was confirmed as VL by a positive result for the rK39 test. Considering the symptoms and signs a combination of VL and secondary hemophagocytic lymphohistiocytosis (HLH) was suspected. The patient was treated with a 21 mg/kg total dose of AmBisome. The child responded positively to treatment, and HLH syndrome was excluded.\",\"PeriodicalId\":121181,\"journal\":{\"name\":\"International Journal of Tropical Diseases\",\"volume\":\"24 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-06-09\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Journal of Tropical Diseases\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.23937/2643-461x/1710048\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Tropical Diseases","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.23937/2643-461x/1710048","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
A Severe Form of Pediatric Visceral Leishmaniasis - A Case Report
According to the World Health Organization, leishmaniasis is one of the seven most important tropical diseases, and it is a major global health concern. In Armenia, it is a re-emerging disease. We present a case of a one-year-old child from active visceral leishmaniasis (VL) focus with a history of intermittent fever and anemia, progressive weakness, abdominal distension with loss of appetite for 3 months. The case was confirmed as VL by a positive result for the rK39 test. Considering the symptoms and signs a combination of VL and secondary hemophagocytic lymphohistiocytosis (HLH) was suspected. The patient was treated with a 21 mg/kg total dose of AmBisome. The child responded positively to treatment, and HLH syndrome was excluded.