帕金森病的研究进展

Zhang Li
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引用次数: 0

摘要

帕金森病(PD)是一种进行性神经退行性疾病,其特征是位于黑质中含有多巴胺的神经元变性。目前,PD的具体病因和发病机制尚不清楚。目前还没有一个特异、灵敏的预测和早期诊断系统,治疗基本上是对症治疗。随着人口老龄化的加剧,帕金森病的发病率不断上升,给社会经济带来了巨大的挑战。因此,国家和政府对帕金森病的研究越来越重视。中国科技部已批准“神经退行性疾病发病机制及治疗策略研究”和“帕金森病发病机制及治疗策略研究”两项973课题。本文就帕金森病的病因、发病机制、早期诊断体系及治疗策略等方面进行综述。这些结果将有助于我国PD研究的进步。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Progress in Parkinson's disease
Parkinson's disease(PD) is a progressive neurodegenerative disorder, characterized by degeneration of dopamine-containing neurons located in substantia nigra. Up to now, the specific etiology and pathogenesis of PD are unknown. There has not yet a specific, sensitive predictive and early diagnostic system, and treatment is basically symptomatic. The incidence of PD is rising with the increase of aging population, and bringing great challenge to society and economy. So our country and government pay more and more attention to PD research. The Ministry of Science and Technology of China has approved two 973 projects, the Research of Pathogenesis andTreatment Strategy on Neurodegenerative Disease and the Research of Pathogenesis and Treatment Strategies on PD. The review mainly focuses on the etiology, pathogenesis, early diagnostic system and treatment strategies of PD. All the results will contribute to the progress of our country's PD research.
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