肺康复在特发性肺纤维化患者中的作用

E. Danteș, E. Tudorache, M. Man
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引用次数: 3

摘要

特发性肺纤维化(IPF)被认为是最严重的肺部疾病之一,也是肺间质性疾病(ILD)最严重的形式。人们一直关注临床研究,以确定影响这种慢性进行性肺病患者生活质量的新疗法,这些患者的平均生存期为3-5年。尽管近年来新的抗纤维化疗法在减缓疾病的功能衰退方面取得了很大进展,但它未能改变IPF患者的预后和生存。临床试验和最近的ATS/ERS指南提供了至少中等和低水平的证据,证明在ILD患者,特别是IPF患者参加肺部康复计划后,增加了耐受性,减轻了症状,改善了生活质量。肺康复已被证明是COPD患者的标准护理,但其个性化应用于IPF患者已取得积极的短期效果,成为非药物治疗的安全替代方案。本章包括康复计划的总体目标、类型和结构、训练前后患者的复杂评估方法、训练类型以及短期和长期结果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Role of Pulmonary Rehabilitation in Patients with Idiopathic Pulmonary Fibrosis
Idiopathic pulmonary fibrosis (IPF) is known as one of the most severe lung conditions and the worst form of interstitial lung disease (ILD). There is a continu-ing concern about clinical research to identify new therapies that influence the quality of life in patients diagnosed with this chronic progressive pulmonary disease, with an average survival of 3–5 years. Although in recent years great progress has been made to slow down the functional decline of the disease with new antifibrotic therapies, it has failed to alter the prognosis and survival of IPF patients. Clinical tri-als and recent ATS/ERS guidelines have brought at least moderate and low levels of evidence for increased effort tolerance, decreased symptoms, and improved quality of life following participation in lung rehabilitation programs for ILD patients and in particular those with IPF. Pulmonary rehabilitation has been shown to be a standard of care for COPD patients, but their personalized application to patients with IPF has had positive short-term results, becoming a safe alternative to non-pharmacological treatment. The chapter includes the general objectives of rehabilitation programs, their type and structure, ways of complex assessment of patients before and after a training exercise, types of exercises, and short- and long-term results.
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