高度并行集成的微流体生物通道阵列

Technical Digest. MEMS 2001. 14th IEEE International Conference on Micro Electro Mechanical Systems (Cat. No.01CH37090) Pub Date : 2001-01-21 DOI:10.1109/MEMSYS.2001.906572

R.H. Liu, H. Chen, K. Luehrsen, D. Ganser, D. Weston, J. Blackwell, P. Grodzinski

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引用次数: 6

摘要

微流控生物通道阵列将大规模并行微流控通道与摩托罗拉玻璃基微阵列生物芯片集成在一起，已被成功开发。我们证明了这样的设备允许DNA杂交分析在小型化和高度并行的方式进行。生物通道阵列是一种新的DNA诊断平台，它具有一些令人满意的特点，如一次性使用和成本效益，高度并行(并行多达52个协议)，处理速度快。此外，每个阵列只消耗纳升体积(/spl sim/100 nL)的DNA样品/试剂。

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Highly parallel integrated microfluidic biochannel arrays

Microfluidic biochannel arrays that integrates massively parallel microfluidic channels with Motorola glass-based microarray biochips have been successfully developed. We demonstrated that such a device allows DNA hybridization assays to be performed in a miniaturized and highly parallel fashion. The biochannel arrays are a new DNA diagnostics platform that has several desirable features such as single-use and cost-effective, highly parallel (up to 52 protocols in parallel), and processed rapidly. Additionally, only nanoliter-volumes (/spl sim/100 nL) of DNA sample/reagents are consumed per array.

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Technical Digest. MEMS 2001. 14th IEEE International Conference on Micro Electro Mechanical Systems (Cat. No.01CH37090)

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