COVID-19患者的主动脉炎和严重主动脉功能不全

N. Oryshchyn, Y. Ivaniv
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引用次数: 1

摘要

主动脉炎是一种罕见的引起主动脉功能不全的原因,但它应该被认为是主动脉反流的其他原因之一。在COVID-19大流行期间,报告了许多自身免疫性大动脉炎病例。我们提出了一个病例报告的大动脉炎与严重的主动脉功能不全,这是在一个轻度形式的冠状病毒感染和关节炎发作后发展的病人。超声心动图显示严重的主动脉反流,胸主动脉扩张和主动脉壁增厚。超声检查显示颈动脉壁增厚。计算机断层扫描证实了主动脉炎的诊断。c反应蛋白升高提示急性炎症过程。甲强的松龙治疗主动脉炎,临床反应良好。本文讨论了引起主动脉炎的可能原因:高须动脉炎、巨细胞动脉炎、强直性脊柱炎和多软骨炎。在排除了所有可能的原因后,诊断为冠状病毒感染引起的自身免疫过程。讨论了与COVID-19相关的患者动脉炎病例。多模式诊断(超声心动图、增强计算机断层扫描、主动脉分支超声)在检测主动脉病变和评估主动脉炎病理过程的程度方面发挥着核心作用。需要实验室检查以确定主动脉炎的原因。最终的诊断应结合临床表现、诊断和实验室检查结果进行分析。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
AORTOARTERITIS AND SEVERE AORTIC INSUFFI CIENCY IN A PATIENT AFTER COVID-19
Aortoarteritis is a rare cause of the aortic insuffi ciency, but it should be considered among the other causes of aortic regurgitation. A number of cases of autoimmune aortoarteritis have been reported during the COVID-19 pandemic. We present a case report of aortoarteritis with severe aortic insuffi ciency, which developed in a patient after a mild form of coronavirus infection and an episode of arthritis. Echocardiography revealed severe aortic regurgitation, dilatation of the thoracic aorta and thickening of the aortic walls. Ultrasonography showed thickening of the carotid arterial walls. Computed tomography confi rmed the diagnosis of aortoarteritis. Elevated C-reactive protein indicated an acute infl ammatory process. Aortoarteritis was treated with methylprednisolone with good clinical response. Possible causes of aortoarteritis are discussed: Takayasu arteritis, giant cell arteritis, ankylosing spondylitis and polychondritis. After exclusion of all possible causes, aortoarteritis in the patient was diagnosed as an autoimmune process caused by coronavirus infection. Cases of arteritis in patients related to COVID-19 are discussed. Multimodality diagnostics (echocardiography, contrast-enhanced computed tomography, ultrasonography of aortic branches) play a central role in detecting aortic lesions and evaluating the extent of the pathological process in aortitis. A laboratory workup is needed to identify the cause of the aortitis. The fi nal diagnosis should be made on the analysis of clinical manifestations, diagnostic and laboratory fi ndings.
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