[1-乙氧基硅烷抑溃疡作用的可能机制分析]。

Izvestiia Akademii nauk SSSR. Seriia biologicheskaia Pub Date : 1991-07-01

M M Rasulov, I G Kuznetsov, L K Bartkova, S K Suslova, A A Belousov, M G Voronkov

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引用次数: 0

摘要

研究了1-乙氧基硅烷对实验性胃溃疡大鼠愈合过程的刺激作用。1-乙氧基硅烷抑制血液和胃壁组织脂质过氧化，与人工膜相互作用，影响肝脏线粒体呼吸速率。本文对1-乙氧基硅烷的趋膜作用提出了一种假说，该假说是其抑溃疡作用的基础。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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[An analysis of the possible mechanism of the ulcerostatic action of 1-ethoxysilatrane].

Stimulating effect of 1-ethoxysilatrane on healing processes of experimental stomach ulcers was studied in rats. 1-ethoxysilatrane inhibited lipid peroxidation in blood and stomach wall tissues, interacted with artificial membranes, and affected the rate of mitochondrial respiration in liver. A hypothesis is put forward on the membranotropic effect of 1-ethoxysilatrane which underlies its ulcerostatic effect.

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Izvestiia Akademii nauk SSSR. Seriia biologicheskaia

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