3例常染色体显性多囊肾病患者在肾切除术并同时植入腹膜导尿管后开始腹膜透析。

L. Lelandais, C. Roubiou, C. Courivaud, G. Guichard, J. Barkatz, Catherine Bressson-Vautrin
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摘要

由于常染色体显性多囊肾病(ADPKD),当终末期肾病(ESRD)患者需要肾切除术准备肾移植时,腹膜透析(PD)的开始是困难的。本文描述了3例于2017年和2018年在贝桑顿肾内科病房随访的因ADPKD引起的ESRD的成年患者,这些患者在肾切除术后开始腹膜透析并同时植入腹膜导管。回顾性收集资料。在纳入的3例患者中,所有患者在手术后的第一个月内开始PD,不需要血液透析。从肾切除术到PD开始的平均延迟时间为8.7天。采用小容积(1.5L)连续动态PD (CAPD)技术开始肾脏替代治疗,然后采用小容积自动PD (APD)技术进行肾脏替代治疗。从肾切除术到建立标准APD计划的平均延迟为24.3天。在PD建立时没有重大并发症的报道,特别是没有透析液泄漏。从长期来看,技术生存率很好,因为2例患者仍在接受PD治疗,而1例患者已移植。充分性标准令人满意。综上所述,我们这3例患者在多囊患者肾切除术并发PD导管植入术后PD开始的结果非常有趣。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Case report about three patients affected by autosomal dominant polycystic kidney disease who started peritoneal dialysis after nephrectomy and simultaneous peritoneal catheter implantation.
Peritoneal dialysis (PD) initiation can be difficult in patients developing end stage renal disease (ESRD) due to autosomal dominant polycystic kidney disease (ADPKD) when these patients need nephrectomy to prepare kidney transplantation. Here we describe the cases of 3 adult patients followed in the nephrology ward of Besançon in 2017 and 2018 for ESRD due to ADPKD and who began peritoneal dialysis in the post-operative period following nephrectomy with simultaneous peritoneal catheter implantation. The data were collected retrospectively.Among the three patients included, all began PD during the first month after being operated on, without requiring hemodialysis. Mean delay between nephrectomy and PD start was 8.7 days. The renal-replacement therapy was begun following a continuous ambulatory PD (CAPD) technique with small volumes (1.5L), then was carried on with automated PD (APD) technique with small volumes. The mean delay between nephrectomy and the establishment of a standard APD program was 24.3 days. No major complications were reported at the establishment of PD, particularly there were no dialysate leaks. On a long term view, technical survival was good since 2 patients are still treated by PD whereas one patient has been transplanted. Adequacy criteria were satisfactory. To conclude, our group of 3 patients shows very interesting results about PD start in the post-operative period after nephrectomy with simultaneous PD catheter implantation in polycystic patients.
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