纳米植物治疗癌症

Magdalena Pérez Ortiz, Angélica Guerrero-Castilla, E. C. Quispe Chávez
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引用次数: 0

摘要

植物化学物质被认为具有有益健康的特性,主要是它们的抗癌潜力。癌症治疗寻求缩小肿瘤并杀死癌细胞;然而,由于耐药细胞系的出现,现有的常规治疗经常失败。植物源性化合物因其潜在的抗癌作用或作为常规治疗的辅助药物而被研究。然而,植物化合物的一些物理化学性质和稳定性特征给生物制药带来了困难,限制了它们在肿瘤学中的疗效和临床应用。从这个意义上说,纳米医学为开发生物相容性、可生物降解、安全和有效的植物制剂提供了另一种选择。纳米结构的给药系统通过改善植物化合物的物理化学和生物制药性质以及提高治疗效果,提供了传统剂型的更好替代品,在植物药物的生物利用度方面显示出巨大的潜力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Nanophytotherapeutics for Cancer
Phytochemicals have been attributed beneficial health properties, mainly their anticancer potential. Cancer treatment seeks to shrink the tumor and kill cancer cells; however, the conventional treatment available frequently fails due to the emergence of drug-resistant cell lines. Plant-derived compounds have been studied for their potential anticancer effects or as adjuvant drug to conventional treatment. However, some of the physicochemical properties and stability characteristics of the phytocompounds generate biopharmaceuticals difficulties that limit their efficacy and clinical applications in oncology. In this sense, nanomedicine offers an alternative for the development of biocompatible, biodegradable, safe, and efficacy phytoformulations. Nanostructured delivery systems show immense potential in the bioavailability of phytodrugs by providing better alternatives to conventional dosage forms, through improving physicochemical and biopharmaceutical properties of the phytocompounds and along with it to enhance the therapeutic efficacy.
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