雅加达地区真菌多样性及酵母菌对几种抗真菌药的敏感性

C. R. Tjampakasari, Yeva Rosana, Mardiastuti Hw
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引用次数: 0

摘要

真菌感染在热带地区很常见。真菌病的病因取决于病因和伴随的危险因素。重要的是进行培养和鉴定以确定病因,并继续进行抗真菌敏感性检查以确定适当的处理。治疗酵母菌感染的方法取决于感染的类型、严重程度和受感染的身体部位。由于各种真菌引起感染,使用的抗真菌药物也非常多样化。该研究于2020年进行,包括各种标本的350个样本,阳性培养116个(33.14%)。利用Vitek 2®自动化系统和玻片培养鉴定真菌19种,其中酵母99.14%,霉菌0.87%。酵母菌以白色念珠菌(26.27%)和曲霉菌(Aspergillus sp .)最多;根霉分别为0.86%。酵母对几种抗真菌药物的敏感性模式显示,氟康唑的有效率为96.43%,伏立康唑和两性霉素B的有效率分别为93.24%。其次是氟西菌素、米卡芬净和卡波芬净,分别为91.66%、86.18%和85.74%。需要改进培养、识别和敏感性检查,以获得反映的图像和信息。关键词:酵母菌,霉菌,敏感性模式,抗真菌
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Fungal Diversity and Yeast Patterns of Yeast Sensitifity to Several Antifungals in Jakarta
Fungal infections are common in the tropics. The cause of mycoses depends on the cause and the accompanying risk factors. It is important to do culture and identification to determine the etiology and continue with antifungal sensitivity examination to determine the appropriate management. The method of treating a yeast infection depends on the type of infection, its severity and the part of the body that is infected. As various fungi cause infections, the antifungal drugs used are also very diverse. The study was conducted during 2020 consisting of  350 samples of various specimens with positive cultures of 116 (33.14%). The results of identification using Vitek 2®   automated system and slide culture obtained 19 species on fungus, consistinf of 99.14% yeast and  0.87% mold. The most yeast found were C. albicans 26.27%  and Aspergillus sp;  Rhizopus  0.86 %  respectively from mold. The pattern of sensitivity of yeast to several antifungals showed that Fluconazole was effective at 96.43%, followed Voriconazole and Amphothericin B 93.24% respectively. The next are Flucytocin, Micafungin and Caspofungin 91.66%,  86.18% and 85.74% respectively. Culture, identification and sensitivity examination need to be improved to obtain images and information that reflects.Keywords : yeast, mold, sensitivity patterns, antifungal  
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