声场模拟在纳米药物原位传递超声驱动装置设计中的应用

Long Meng, Chunxiang Jiang, Hai-rong Zheng
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引用次数: 0

摘要

粒子操纵在超声给药、细胞操纵和分子捕获等领域发挥着重要作用。超声操作是一种利用声辐射力的非接触式操作技术。当颗粒悬浮在流体中时,超声波辐射力使颗粒集中在指定的位置。本文报道了一种基于平面内正交驻压波叠加的二维阵列模拟。首先,利用ANSYS有限元分析软件对一维声场进行了仿真。然后,通过修正PZT模型得到二维声场。我们用14v振幅信号在1.5 MHz频率下激励模型时的粒子浓度。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The simulation of acoustic field in the design of ultrasound driving device for site nano-drug delivery
Particle manipulation plays a very important role in many fields, such as ultrasound drug delivery, cell manipulation and trapping molecules. Ultrasonic manipulation, which uses acoustic radiation forces, is a contactless manipulation technique. When the particles suspended in a fluid, the ultrasound radiation forces made the particles concentrate in a designated location. Here it is reported on a simulation for two-dimensional arraying based on the superposition of two in-plane orthogonally oriented standing pressure waves. First, we do the simulation of one-dimensional acoustic field with the FEA software of ANSYS. Then, we got the two-dimensional acoustic field by modify the PZT model. We make the particles concentration when the model was excited with a 14 V amplitude signal at 1.5 MHz.
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