{"title":"富血小板血浆对增生性瘢痕成纤维细胞生成CTGF的影响","authors":"Abdiev Ta, Shaker Og, Hassan Ar, Abdueva Ra","doi":"10.21608/FUMJ.2021.184727","DOIUrl":null,"url":null,"abstract":"Hypertrophic scars are human dermal fibroproliferative disorder that occur following trauma, inflammation, surgery and burns. Connective Tissue Growth Factor (CTGF) is a cysteine-rich mitogen peptide that binds heparin and is secreted by fibroblasts after activation with Transforming Growth Factor beta (TGF ). Platelet-Rich Plasma (PRP) may serve as a source of different growth factors to induce fibrosis in hypertrophic scars.","PeriodicalId":436341,"journal":{"name":"Fayoum University Medical Journal","volume":"31 1","pages":"0"},"PeriodicalIF":0.0000,"publicationDate":"2021-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The Effects of Platelet-Rich Plasma on CTGF Produced by Fibroblasts in Hypertrophic Scars\",\"authors\":\"Abdiev Ta, Shaker Og, Hassan Ar, Abdueva Ra\",\"doi\":\"10.21608/FUMJ.2021.184727\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Hypertrophic scars are human dermal fibroproliferative disorder that occur following trauma, inflammation, surgery and burns. Connective Tissue Growth Factor (CTGF) is a cysteine-rich mitogen peptide that binds heparin and is secreted by fibroblasts after activation with Transforming Growth Factor beta (TGF ). Platelet-Rich Plasma (PRP) may serve as a source of different growth factors to induce fibrosis in hypertrophic scars.\",\"PeriodicalId\":436341,\"journal\":{\"name\":\"Fayoum University Medical Journal\",\"volume\":\"31 1\",\"pages\":\"0\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Fayoum University Medical Journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.21608/FUMJ.2021.184727\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Fayoum University Medical Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.21608/FUMJ.2021.184727","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
The Effects of Platelet-Rich Plasma on CTGF Produced by Fibroblasts in Hypertrophic Scars
Hypertrophic scars are human dermal fibroproliferative disorder that occur following trauma, inflammation, surgery and burns. Connective Tissue Growth Factor (CTGF) is a cysteine-rich mitogen peptide that binds heparin and is secreted by fibroblasts after activation with Transforming Growth Factor beta (TGF ). Platelet-Rich Plasma (PRP) may serve as a source of different growth factors to induce fibrosis in hypertrophic scars.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
