蛋白质微阵列在变态反应性疾病诊断和研究中的应用

R. Hiller
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引用次数: 0

摘要

摘要:对于蛋白质功能、相互作用和丰度的系统和全系统分析,蛋白质微阵列代表了现代高通量蛋白质组学的支柱之一。以高度并行和小型化的方式分析样品的前景推动了在癌症、自身免疫或过敏领域开发新型诊断应用的努力。在这里,我讨论了蛋白质微阵列在诊断1型相关过敏性疾病中用于IgE抗体谱分析的最新进展。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
PROTEIN MICROARRAYS FOR DIAGNOSIS AND RESEARCH OF ALLERGIC DISEASES
Summary: For both the systematic as well as for the system-wide analysis of protein function, interaction and abundance, protein microarrays represent one of the pillars underlying modern high-throughput Proteomics. The prospect of analysing samples in a highly parallel while miniaturized fashion has fuelled efforts to develop novel diagnostic applications in the cancer, autoimmune or allergy field. Here, I discuss recent advancements in the development of protein microarrays for the profiling of IgE antibodies in the diagnosis of Type 1-related allergic diseases.
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